ABSTRACT The synthesis of new α-aminophosphonates 4a-j (diethyl((dialkoxyphosphoryl)(phenyl)methyl)phosphoramidates) were achieved through a one pot simple and efficient method from the three-component condensation reaction (Kabachnik-Fields reaction) of diethyl phosphoramidate, aryl salicylaldehydes, and dialkyl phosphite by using microwave irradiation under solvent-free and catalyst-free conditions in good to excellent yields and short reaction times. The structures of the novel products were established by IR, 1H, 13C & 31P-NMR and Mass spectroscopy. All the synthesized compounds were screened their antimicrobial activity. GRAPHICAL ABSTRACT

中文翻译：

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新型二乙基（（二烷氧基磷酰基）（2-羟基苯基）甲基）氨基磷酸酯的微波辅助合成及抗菌活性

摘要 通过氨基磷酸二乙酯的三组分缩合反应（Kabachnik-Fields 反应），通过一锅简单有效的方法合成了新型 α-氨基膦酸酯 4a-j（二乙基（（二烷氧基磷酰基）（苯基）甲基）氨基磷酸酯）。 、芳基水杨醛和亚磷酸二烷基酯通过在无溶剂和无催化剂的条件下使用微波辐射以良好的收率和较短的反应时间进行。通过红外、1H、13C和31P-NMR和质谱确定了新产物的结构。对所有合成的化合物进行了抗菌活性筛选。图形概要