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Synthesis of Amphiphilic Peptidomimetics Based on the Aliphatic Derivatives of Natural Amino Acids
Moscow University Chemistry Bulletin ( IF 0.7 ) Pub Date : 2020-02-10 , DOI: 10.3103/s0027131419060087 Z. G. Denieva , N. A. Romanova , T. G. Bodrova , U. A. Budanova , Yu. L. Sebyakin
Moscow University Chemistry Bulletin ( IF 0.7 ) Pub Date : 2020-02-10 , DOI: 10.3103/s0027131419060087 Z. G. Denieva , N. A. Romanova , T. G. Bodrova , U. A. Budanova , Yu. L. Sebyakin
Abstract—The paper describes the production of a number of lipoamino acid derivatives based on L-serine, L-ornithine, and L-lysine with potential antibacterial activity. The designed synthesis schemes are distinguished by the simplicity and versatility of the approach used. This allows us to use them to obtain a series of samples in preparative quantities required to perform the subsequent physico-chemical and biochemical studies.
中文翻译:
基于天然氨基酸的脂肪族衍生物合成两亲拟肽
摘要—本文描述了基于L-丝氨酸,L-鸟氨酸和L-赖氨酸的许多脂氨基酸衍生物的生产,这些衍生物具有潜在的抗菌活性。设计的综合方案的特点是所用方法的简单性和多功能性。这使我们能够使用它们来获得一系列所需数量的制备样品,以进行后续的理化和生化研究。
更新日期:2020-02-10
中文翻译:
基于天然氨基酸的脂肪族衍生物合成两亲拟肽
摘要—本文描述了基于L-丝氨酸,L-鸟氨酸和L-赖氨酸的许多脂氨基酸衍生物的生产,这些衍生物具有潜在的抗菌活性。设计的综合方案的特点是所用方法的简单性和多功能性。这使我们能够使用它们来获得一系列所需数量的制备样品,以进行后续的理化和生化研究。