Abstract

An effective, affordable, and rapid method for the analysis of drugs based on chloramphenicol is developed using multisensory digital colorimetry. The use of a two-dimensional code for the identification and quantification of chloramphenicol with the minimum level of informational noise is proposed. The principal component analysis is used to increase the reliability of the results of the determination of the medicinal substance. The adequacy of the developed approach is confirmed by the analysis of chloramphenicol preparations in the form of two dosage forms: tablets and eye drops. The accuracy of the results is confirmed by the standard addition method. The results prove that the preparations do not have statistically significant differences from the values declared by the manufacturer.

中文翻译：

---

药物中氯霉素的多感官数字比色法鉴定与定量

摘要

使用多传感器数字比色法开发了一种有效，可负担且快速的基于氯霉素的药物分析方法。提出了使用二维代码对氯霉素进行鉴定和定量的同时，将信息噪声降至最低水平。主成分分析用于提高药物含量测定结果的可靠性。通过分析两种剂型形式的氯霉素制剂证实了所开发方法的充分性：片剂和滴眼剂。结果的准确性通过标准添加方法确认。结果证明该制剂与制造商声明的值没有统计学上的显着差异。