The influence of selenium dioxide on bioglass in (45.0-x) SiO₂ 24.5Na₂O 24.5CaO 6.0P₂O₅ xSeO₂ (x = 0.0, 0.5, 1.0, 1.5, and 2.0 wt%) system was investigated by preparing the glass through conventional melting and annealing method. The glass transition temperature (Tg), crystallization temperature (Tc), and density of prepared glasses were measured by differential thermal analysis and Archimedes’ principle respectively. The structural and microstructure analyses of glasses were characterized by Raman spectroscopy, Fourier transformed infrared (FTIR) spectroscopy, and scanning electron microscopy (SEM) with energy dispersive X-ray analysis (EDX). The formation of hydroxy apatite carbonate (HCA) layer for glasses was investigated by Raman spectroscopy, FTIR, SEM with EDS, pH measurement, ion concentrations analysis, and (%) weight loss after immersion in simulated body fluid (SBF) for 10 h to 14 days at 37.5°C. Experimental results showed that SeO₂ substitution for SiO₂ in the glass had increased glass density and molar volume whereas network connectivity was decreased. The addition of selenium oxide reduced the glass transition temperature and also crystallization temperature. The FTIR study of glass confirmed the P–O bonding after immersion for 14 days in SBF, which was also identified in the Raman spectroscopy. SEM of the 14 days immersed sample showed the formation of cauliflower like morphology of HA particles on the glass. pH and ion concentrations analysis also confirmed the formation of HCA layer after 14 days of immersion in SBF.

中文翻译：

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二氧化硒（SeO 2）对SiO 2 -Na 2 O-CaO-P 2 O 5体系中生物玻璃性能的影响

二氧化硒对（45.0-x）SiO ₂ 24.5Na ₂ O 24.5CaO 6.0P ₂ O ₅ xSeO ₂（x 通过常规的熔融和退火方法制备玻璃，研究＝（0.0、0.5、1.0、1.5和2.0wt％）体系。分别通过差热分析和阿基米德原理测量所制备的玻璃的玻璃化转变温度（Tg），结晶温度（Tc）和密度。通过拉曼光谱，傅立叶变换红外（FTIR）光谱和具有能量色散X射线分析（EDX）的扫描电子显微镜（SEM）来表征玻璃的结构和微观结构。通过拉曼光谱，FTIR，带EDS的SEM，pH测量，离子浓度分析以及在模拟体液（SBF）中浸泡10 h至（h）的重量损失，研究了玻璃的羟基磷灰石碳酸（HCA）层的形成。在37.5°C下放置14天。玻璃中的SiO ₂替代_2可以增加玻璃密度和摩尔体积，而降低网络连通性。氧化硒的添加降低了玻璃化转变温度以及结晶温度。玻璃的FTIR研究证实了在SBF中浸泡14天后的P-O键，这在拉曼光谱学中也可以确定。浸没样品14天的SEM显示玻璃上HA颗粒形成花椰菜状的形态。pH和离子浓度分析也证实了在SBF中浸泡14天后HCA层的形成。