One challenge of bone defect repair is the promotion of blood vessel formation. Many of the current methods promote vascularisation by adding specific growth factors to materials used for bone healing. However, the high cost and fast inactivation of the growth factors and angiogenic cells have limited the clinical use of such systems. Zhang et al. report the fabrication of a covalently cross‐linked aminated bioactive glass nanoparticle‐chondroitin sulfate methacrylate organic‐inorganic composite hydrogel with angiogenic properties. The mechanical properties are well suited for bone repair materials; simultaneously the local pH stability and sustained ion release of the hydrogel are conducive to cell adhesion, proliferation and angiogenesis. (DOI: 10.1002/bip.23328)

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骨缺损修复的挑战之一是促进血管形成。当前的许多方法都通过向骨愈合材料中添加特定的生长因子来促进血管形成。然而，生长因子和血管生成细胞的高成本和快速失活限制了这种系统的临床使用。张等。报告了具有血管生成特性的共价交联胺化生物活性玻璃纳米颗粒硫酸软骨素甲基丙烯酸酯有机无机复合水凝胶的制备。机械性能非常适合于骨修复材料。同时水凝胶的局部pH稳定性和离子的持续释放有利于细胞粘附，增殖和血管生成。（DOI：10.1002 / bip.23328）