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COMPARISON OF STATIC POSTURAL BALANCE IN PATIENTS WITH SWEDDS AND PARKINSON’S DISEASE
Journal of Mechanics in Medicine and Biology ( IF 0.8 ) Pub Date : 2020-09-07
DO-YOUNG KWON, YOON-HYEOK CHOI, YU-RI KWON, GWANG-MOON EOM, JI-WON KIM

Differentiating scans without evidence of dopaminergic deficits (SWEDDs) from Parkinson’s disease (PD) is very important to avoid costly and inappropriate interventions. The postural balance strategy patients with SWEDDs are not clear. This study investigates the difference in static postural balance between patients with SWEDDs and PD. Twenty-two patients (11 SWEDDs and 11 PD groups) and 11 control groups were instructed to quietly stand on a custom-made force platform. The outcome measures were, mean distance, 95% confidence ellipse area, mean velocity, mean frequency, peak frequency and peak power derived from the center of pressure (COP) data in overall, medio-lateral (ML) and anterio-posterior (AP) directions. As statistical analysis, ANOVA and post hoc tests were conducted for comparison of patients with SWEDDs and PD. SWEDDs patients presented a smaller postural sway size and a more frequent postural sway mainly in the ML direction (p<0.05). On the contrary, there were no significant differences in mean velocity and peak power. Also, no significant differences existed between SWEDDs and normal subjects (p>0.05). The results reflect that a few COP-based outcome variables might be useful to distinguish SWEDDs patients from PD patients. This study suggests that a static postural balance test can be used for clinical screening and identification of potential SWEDDs.



中文翻译:

瑞典裔和帕金森氏病患者静态体位平衡的比较

区分没有多巴胺能缺乏症(SWEDDs)和帕金森氏病(PD)的证据的扫描对避免昂贵且不合适的干预非常重要。SWEDDs的姿势平衡策略患者尚不清楚。这项研究调查了SWEDDs和PD患者之间静态姿势平衡的差异。指示22名患者(11个SWEDD和11个PD组)和11个对照组静静地站在定制的部队平台上。结果量度为:平均距离,95%置信椭圆面积,平均速度,平均频率,峰值频率和峰值功率,其取自总体的压力中心(COP)数据,中外侧(ML)和前后(AP) )路线。作为统计分析,进行了ANOVA和事后检验,以比较SWEDD和PD患者。p<005)。相反,平均速度和峰值功率没有显着差异。此外,SWEDD与正常受试者之间也没有显着差异(p>005)。结果表明,一些基于COP的结果变量可能有助于区分SWEDDs患者和PD患者。这项研究表明,静态姿势平衡测试可用于临床筛查和识别潜在的SWEDD。

更新日期:2020-09-11
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