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DIFFERENCES IN GAIT PATTERNS BETWEEN PATIENTS WITH SWEDD AND NORMAL SUBJECTS
Journal of Mechanics in Medicine and Biology ( IF 0.8 ) Pub Date : 2020-09-07
DO-YOUNG KWON, YU-RI KWON, YOON-HYEOK CHOI, JIN-YOUNG HA, SANG-HYUK KIM, GWANG-MOON EOM, JI-WON KIM

Whether gait assessment can distinguish patients with scans without evidence of dopaminergic deficit (SWEDD) from normal individuals remains unclear. In the present study, the gait patterns in SWEDD patients and normal individuals were investigated. 10 patients with SWEDD and 10 healthy normal subjects were recruited. A GaitRite linear walkway was used to quantitatively assess level walking. Eight spatiotemporal variables were selected for comparison between two groups. For statistical analysis, independent sample t-tests were performed to compare between normal individuals and SWEDD patients. Compared with normal individuals, SWEDD patients exhibited a shorter step length (p<0.001). In addition, SWEDD patients showed a wider distribution of heel-to-heel (HH) base of support compared with normal individuals (p<0.000). SWEDD patients had a tendency to deteriorated gait speed (p=0.072) and double-limb support cycle (p=0.088). These results indicate that SWEDD patients adopted a walking strategy that utilized increased step length and width to compensate for deteriorated dynamic balance. These results indicate that quantitative gait assessment could be useful for more accurate diagnosis of SWEDD patients. In addition, understanding clinical features of SWEDD patients might contribute to efficient interventions.



中文翻译:

患病对象和正常对象的步态差异

步态评估是否可以将没有多巴胺能缺乏症(SWEDD)证据的扫描患者与正常人区分开,目前尚不清楚。在本研究中,调查了SWEDD患者和正常人的步态模式。招募了10名SWEDD患者和10名健康正常受试者。使用GaitRite线性人行道来定量评估水平步行。选择了八个时空变量用于两组之间的比较。用于统计分析,独立样本Ť进行了测试以比较正常人和SWEDD患者。与正常人相比,SWEDD患者的步长较短(p<0001个)。此外,与正常人相比,SWEDD患者的足跟跟(HH)支持基础分布更广泛(p<0000)。SWEDD患者有步态速度下降的趋势(p=0072)和双脚支撑周期(p=0088)。这些结果表明,SWEDD患者采用了步行策略,该策略利用增加的步长和步幅来补偿动态平衡的恶化。这些结果表明定量步态评估对于SWEDD患者的更准确诊断可能有用。此外,了解SWEDD患者的临床特征可能有助于有效的干预。

更新日期:2020-09-11
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