Antibiotics are extensively discharged into the environment through sewages. These emergent contaminants cause health and environmental risks by toxicity, allergic impacts, non-biodegradability and more importantly advancing antibiotic resistance. Antibiotics are hardly removed by conventional treatment processes and frequently are being reported in aquatic environments. The systematic review outlined in this protocol will compile and synthesize literature on the variety and concentrations of antibiotics in wastewaters and receiving water resources. Also, the review will address the efficiency of treatment processes in elimination of antibiotics from aqueous solutions. Outcomes of the study could help wastewater treatment plant engineers with providing reliable design data and outline a road map for future researches. The review will be performed according to the Collaboration for Environmental Evidence (CEE) guidelines for systematic review and evidence synthesis in environmental management, and will be reported according to ROSES reporting standards for systematic evidence syntheses. The published articles will be screened by considering the defined inclusion and exclusion criteria at the title, abstract and full-text levels. Included studies will be exposed to a critical appraisal for validity and quality assessment. The articles will be assessed on the susceptibility to bias and the studies with high bias will be excluded from the data synthesis. The data from included studies will be combined into a narrative synthesis. Random effect Meta-analysis will be conducted due to the likely range of underlying effects. If the heterogeneity exists, the source of heterogeneity will be sought by met-regression and subgroup analyses.

中文翻译：

---

医院和市政废水以及接收水体中抗生素的多样性以及通过处理过程的去除效率：系统的审查方案

抗生素通过污水大量排放到环境中。这些新出现的污染物通过毒性，过敏性影响，不可生物降解性以及更重要的是对抗生素的耐药性造成健康和环境风险。抗生素很难通过常规处理方法去除，并且经常在水生环境中被报道。该方案概述的系统评价将汇编和综合有关废水和接收水资源中抗生素的种类和浓度的文献。此外，该评论还将探讨从水溶液中消除抗生素的治疗过程效率。研究结果可以帮助废水处理厂工程师提供可靠的设计数据，并勾勒出未来研究的路线图。审查将根据环境证据协作（CEE）指南进行，以进行环境管理中的系统审查和证据综合，并根据ROSES报告标准进行报告，以进行系统证据综合。将通过在标题，摘要和全文级别考虑定义的包含和排除标准来筛选已发布的文章。纳入的研究将接受有效性和质量评估的严格评估。将对文章的偏倚敏感性进行评估，并将具有高度偏倚的研究排除在数据综合之外。来自纳入研究的数据将被合并为叙述性综合。由于潜在效应的可能范围，将进行随机效应荟萃分析。如果存在异质性，