Neurologic complications are being recognized as important outcomes of coronavirus disease 2019 (COVID-19). Pathogenesis is varied and incompletely understood, and may include neuroinvasion, indirect post-infectious neuroinflammation, and cerebrovascular pathologies. We present a case of COVID-19-related encephalomyeloradiculitis with clinical and magnetic resonance imaging characteristics of neuromyelitis optica spectrum disorders that was associated with anti-aquaporin-4 antibodies. Our case suggests post-infectious autoimmunity as a mechanism in at least a subset of patients with COVID-19-related neurologic disease.

中文翻译：

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与脑脊髓神经根炎相关的 COVID-19 和抗水通道蛋白 4 抗体阳性：原因还是巧合？

神经系统并发症被认为是 2019 年冠状病毒病 (COVID-19) 的重要结果。发病机制多种多样且尚未完全了解，可能包括神经侵袭、间接感染后神经炎症和脑血管病变。我们介绍了一例 COVID-19 相关脑脊髓神经根炎病例，具有与抗水通道蛋白 4 抗体相关的视神经脊髓炎谱系疾病的临床和磁共振成像特征。我们的案例表明，感染后自身免疫是至少一部分 COVID-19 相关神经系统疾病患者的机制。