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Coronavirus disease 2019 and cardiovascular implications.
Journal of Cardiovascular Medicine ( IF 2.9 ) Pub Date : 2020-10-01 , DOI: 10.2459/jcm.0000000000001068
Silvia Frattini 1 , Gloria Maccagni 2 , Leonardo Italia 2 , Marco Metra 2 , Gian B Danzi 1
Affiliation  

 

The coronavirus disease 2019 (COVID-19) has important implications for the cardiovascular care of patients. COVID-19 interacts with the cardiovascular system on multiple levels, increasing morbidity in patients with underlying cardiovascular conditions and favoring acute myocardial injury and dysfunction. COVID-19 infection may also have long-term implications for overall cardiovascular health. Many issues regarding the involvement of the cardiovascular system remain controversial. Despite angiotensin-converting enzyme 2 serving as the site of entry of the virus into the cells, the role of angiotensin-converting enzyme inhibitors or AT1 blockers requires further investigation. Therapies under investigation for COVID-19 may have cardiovascular side effects. Treatment of COVID-19, especially the use of antivirals, must be closely monitored. This article is a review of the most updated literature.



中文翻译:

冠状病毒疾病2019及其对心血管的影响。

 

冠状病毒病2019(COVID-19),对心血管患者的治疗具有重要意义。COVID-19与心血管系统在多个层面上相互作用,增加了潜在心血管疾病患者的发病率,并促进了急性心肌损伤和功能障碍。COVID-19感染对整体心血管健康也可能有长期影响。关于心血管系统受累的许多问题仍然存在争议。尽管血管紧张素转换酶2充当病毒进入细胞的位点,但血管紧张素转换酶抑制剂或AT1阻滞剂的作用仍需进一步研究。正在研究中的COVID-19疗法可能会产生心血管副作用。必须密切监测COVID-19的治疗,尤其是抗病毒药的使用。本文是对最新文献的回顾。

更新日期:2020-09-11
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