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Withdrawal: Increased expression of fibroblast growth factor 21 (FGF21) during chronic undernutrition causes growth hormone insensitivity in chondrocytes by inducing leptin receptor overlapping transcript (LEPROT) and leptin receptor overlapping transcript-like 1 (LEPROTL1) expression.
Journal of Biological Chemistry ( IF 4.0 ) Pub Date : 2020-09-11 , DOI: 10.1074/jbc.w120.015607 Shufang Wu , Tal Grunwald , Alexei Kharitonenkov , Julie Dam , Ralf Jockers , Francesco De Luca
Journal of Biological Chemistry ( IF 4.0 ) Pub Date : 2020-09-11 , DOI: 10.1074/jbc.w120.015607 Shufang Wu , Tal Grunwald , Alexei Kharitonenkov , Julie Dam , Ralf Jockers , Francesco De Luca
VOLUME 288 (2013) PAGES 27375–27383This article has been withdrawn by Shufang Wu, Alexei Kharitonenkov, Julie Dam, Ralf Jockers, and Francesco De Luca. Tal Grunwald could not be reached. In Fig. 1C, lanes 1 and 2 of the actin immunoblot are the same as lanes 3 and 4. In Fig. 2C, lanes 1 and 4 of the LEPROT immunoblot are the same, and lanes 1 and 3 of the LEPROTL1 immunoblot are the same. There is also a splice in the LEPROTL1 immunoblot.The withdrawing authors affirm that all the experimental results and conclusions reported in this manuscript accurately reflect the experimental work carried out in their laboratory. However, given the issues listed above, the withdrawing authors wish to withdraw this article to preserve the full accuracy of the published scientific literature.
中文翻译:
戒断:慢性营养不良期间成纤维细胞生长因子21(FGF21)的表达增加,通过诱导瘦素受体重叠转录本(LEPROT)和瘦素受体重叠转录样1(LEPROTL1)表达,导致软骨细胞中生长激素不敏感。
卷288(2013)27375–27383页Shufang Wu,Alexei Kharitonenkov,Julie Dam,Ralf Jockers和Francesco De Luca撤回了本文。无法到达Tal Grunwald。在图1C中,肌动蛋白免疫印迹的泳道1和2与泳道3和4相同。在图2C中,LEPROT免疫印迹的泳道1和4是相同的,而LEPROTL1免疫印迹的泳道1和3是相同的。相同。LEPROTL1免疫印迹中也有一个接头。退出的作者确认,该手稿中报告的所有实验结果和结论均准确反映了其实验室中进行的实验工作。但是,鉴于上述问题,撤稿作者希望撤回本文,以保留已发表的科学文献的全部准确性。
更新日期:2020-09-11
中文翻译:
![](https://scdn.x-mol.com/jcss/images/paperTranslation.png)
戒断:慢性营养不良期间成纤维细胞生长因子21(FGF21)的表达增加,通过诱导瘦素受体重叠转录本(LEPROT)和瘦素受体重叠转录样1(LEPROTL1)表达,导致软骨细胞中生长激素不敏感。
卷288(2013)27375–27383页Shufang Wu,Alexei Kharitonenkov,Julie Dam,Ralf Jockers和Francesco De Luca撤回了本文。无法到达Tal Grunwald。在图1C中,肌动蛋白免疫印迹的泳道1和2与泳道3和4相同。在图2C中,LEPROT免疫印迹的泳道1和4是相同的,而LEPROTL1免疫印迹的泳道1和3是相同的。相同。LEPROTL1免疫印迹中也有一个接头。退出的作者确认,该手稿中报告的所有实验结果和结论均准确反映了其实验室中进行的实验工作。但是,鉴于上述问题,撤稿作者希望撤回本文,以保留已发表的科学文献的全部准确性。