Metal ion‐mediated assembly of peptides is an intriguing method for developing novel biomaterials. In particular, peptide building blocks based on collagen triple helical and coiled‐coil peptides have been functionalized with metal‐binding ligands and assemble into hierarchical structures with diverse potential applications. This review outlines the use of metal‐mediated assembly with these supramolecular structures and highlights how changes in the building blocks lead to significant differences in structural morphologies, with the identity of the metal‐binding ligands and their placement on the building block as crucial aspects in the bottom‐up development of the assemblies.

中文翻译：

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金属离子介导的超分子组装中胶原三螺旋和卷曲螺旋肽结构单元的比较

金属离子介导的肽组装是开发新型生物材料的一种有趣方法。尤其是，基于胶原三螺旋和卷曲螺旋肽的肽构建基块已通过金属结合配体进行了功能化，并组装成具有各种潜在应用的层次结构。这篇综述概述了金属介导的组装与这些超分子结构的使用，并着重强调了结构单元的变化如何导致结构形态的显着差异，其中金属结合配体的身份及其在结构单元中的位置是关键的方面。程序集的自下而上的开发。