Sensing technology for heavy metal detection is very crucial for recent decades as the detection method is very easy, rapid, and does not require any pre-treatment of the sample. Nickel is a trace element in the human body and basically a moderate toxic element. There is a limited number of chemo and fluoro sensors reported for nickel as compared to other transition metal ion. Therefore, there is a need for the detailed structure and property studies of the nickel-probes as the knowledge can help in the upcoming development of probes for the nickel. In this review, we have discussed about different colorimetric, fluorimetric and fluorescent chemosensor and their structure, characterization, detection limit, association constant, media, and bio-imaging studies if they are active.

近几十年来，用于重金属检测的传感技术非常关键，因为该检测方法非常容易，快速并且不需要对样品进行任何预处理。镍是人体中的微量元素，基本上是中等毒性元素。与其他过渡金属离子相比，报告的镍化学和氟传感器数量有限。因此，需要对镍探针进行详细的结构和性能研究，因为该知识可以帮助即将开发的镍探针。在这篇综述中，我们讨论了不同的比色，荧光和荧光化学传感器及其结构，特征，检测限，缔合常数，介质和生物成像研究（如果有活性的话）。