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Current and potential biotechnological applications of odorant-binding proteins.
Applied Microbiology and Biotechnology ( IF 3.9 ) Pub Date : 2020-09-05 , DOI: 10.1007/s00253-020-10860-0
Nathália F Brito 1 , Daniele S Oliveira 1 , Thaisa C Santos 1 , Monica F Moreira 1, 2 , Ana Claudia A Melo 1, 2
Affiliation  

Odorant-binding proteins (OBPs) are small soluble proteins whose biological function is believed to be facilitating olfaction by assisting the transport of volatile chemicals in both vertebrate and insect sensory organs, where they are secreted. Their capability to interact with a broad range of hydrophobic compounds combined with interesting features such as being small, stable, and easy to produce and modify, makes them suitable targets for applied research in various industrial segments, including textile, cosmetic, pesticide, and pharmaceutical, as well as for military, environmental, health, and security field applications. In addition to reviewing already established biotechnological applications of OBPs, this paper also discusses their potential use in prospecting of new technologies. The development of new products for insect population management is currently the most prevailing use for OBPs, followed by biosensor technology, an area that has recently seen a significant increase in studies evaluating their incorporation into sensing devices. Finally, less typical approaches include applications in anchorage systems and analytical tools. KEY POINTS: • Odorant-binding proteins (OBPs) present desired characteristics for applied research. • OBPs are mainly used for developing new products for insect population control. • Incorporation of OBPs into chemosensory devices is a growing area of study. • Less conventional uses for OBPs include anchorage systems and analytical purposes. Graphical Abstract.

中文翻译:

气味结合蛋白的当前和潜在的生物技术应用。

气味结合蛋白(OBP)是小的可溶性蛋白,其生物学功能被认为可通过协助挥发性化学物质在脊椎动物和昆虫感觉器官(分泌它们的地方)的运输而促进嗅觉。它们具有与多种疏水化合物相互作用的能力,并具有有趣的特征,如小巧,稳定,易于生产和改性,使其成为各种工业领域(包括纺织,化妆品,农药和制药)应用研究的合适目标,以及军事,环境,健康和安全领域的应用。除了审查已确定的OBP的生物技术应用之外,本文还讨论了其在新技术的勘探中的潜在用途。目前,用于昆虫种群管理的新产品的开发是OBP最主要的用途,其次是生物传感器技术,该领域最近在评估将其结合到传感设备中的研究中得到了显着增长。最后,不太典型的方法包括锚固系统和分析工具中的应用。要点:•气味结合蛋白(OBP)具有应用研究所需的特征。•OBP主要用于开发用于昆虫种群控制的新产品。•将OBP结合到化学传感装置中是一个正在研究的领域。•OBP的较少常规用途包括锚固系统和分析目的。图形概要。该领域最近在评估将其结合到传感设备中的研究中显着增加。最后,不太典型的方法包括锚固系统和分析工具中的应用。要点:•气味结合蛋白(OBP)具有应用研究所需的特征。•OBP主要用于开发用于昆虫种群控制的新产品。•将OBP掺入化学感应装置中是一个正在研究的领域。•OBP的较少常规用途包括锚固系统和分析目的。图形概要。该领域最近在评估将其结合到传感设备中的研究中得到了显着增长。最后,不太典型的方法包括锚固系统和分析工具中的应用。要点:•气味结合蛋白(OBP)具有应用研究所需的特征。•OBP主要用于开发用于昆虫种群控制的新产品。•将OBP结合到化学传感装置中是一个正在研究的领域。•OBP的较少常规用途包括锚固系统和分析目的。图形概要。•OBP主要用于开发用于昆虫种群控制的新产品。•将OBP结合到化学传感装置中是一个正在研究的领域。•OBP的较少常规用途包括锚固系统和分析目的。图形概要。•OBP主要用于开发用于昆虫种群控制的新产品。•将OBP结合到化学传感装置中是一个正在研究的领域。•OBP的较少常规用途包括锚固系统和分析目的。图形概要。
更新日期:2020-09-05
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