The Developmental Origins of Health and Disease (DOHaD) hypothesis derives from the epidemiological and basic/mechanistic health sciences. This well‐supported hypothesis holds that environment during the earliest stages of life—pre‐conception, pregnancy, infancy—shapes developmental trajectories and ultimately health outcomes across the lifespan. Evolutionary anthropologists from multiple subdisciplines are embracing synergies between the DOHaD framework and developmentalist approaches from evolutionary biology. Even wider dissemination and employment of DOHaD concepts will benefit evolutionary anthropological research. Insights from experimental DOHaD work will focus anthropologists' attention on biochemical/physiological mechanisms underpinning observed links between growth/health/behavioral outcomes and environmental contexts. Furthermore, the communication tools and wide public appeal of developmentalist health scientific research may facilitate the translation/application of evolutionary anthropological findings. Evolutionary Anthropology, in turn, can increase mainstream DOHaD research's use of evolutionary theory; holistic, longitudinal, and community‐based perspectives; and engagement with populations whose environmental exposures differ from those most commonly studied in the health sciences.

中文翻译：

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健康与疾病的发展起源框架与进化人类学的多个分支之间的协同作用。

健康与疾病的发展起源（DOHaD）假设源自流行病学和基础/机械健康科学。这个得到充分支持的假设认为，生命的早期阶段（受孕前，怀孕，婴儿期）的环境会影响整个生命周期的发展轨迹并最终影响健康。来自多个子学科的进化人类学家正在拥抱DOHaD框架与来自进化生物学的发展主义方法之间的协同作用。DOHaD概念的更广泛传播和运用将有益于进化人类学研究。DOHaD实验性工作的见解将使人类学家将注意力集中在生物化学/生理机制上，这些机制将支撑观察到的增长/健康/行为结果与环境之间的联系。此外，发展主义卫生科学研究的交流工具和广泛的公众吸引力可能会促进进化人类学研究结果的翻译/应用。反过来，进化人类学可以增加主流DOHaD研究对进化理论的使用。整体，纵向和基于社区的观点; 以及与环境接触不同于健康科学中最常研究的人群的接触。