This report discusses a case of a 75-year-old female patient with metachronous multicentric carcinomas in the oral cavity at 4 different sites. In this patient, there were no generally associated characteristics, such as drinking alcohol, chewing betel quid or smoking cigarettes. However, her elder sister died due to oral carcinoma. Although well-known risk factors for oral carcinoma were not detected, a previous family history was found. These findings suggest the potential for an unknown genetic anomaly associated with oral carcinoma. This is the first report to describe a female patient with oral multicentric carcinoma arising from four different sites.

中文翻译：

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一名女性患者来自四个不同部位的口腔多中心癌。

本报告讨论了一名75岁的女性患者，该患者在4个不同部位的口腔中患有异时性多中心癌。在该患者中，没有一般相关的特征，例如饮酒，嚼槟榔或吸烟。然而，她的姐姐死于口腔癌。尽管未发现众所周知的口腔癌危险因素，但已有家族史。这些发现表明与口腔癌相关的未知遗传异常的可能性。这是第一份描述一名女性患者的报告，该患者患有四个不同部位的口腔多中心癌。