Antiretroviral therapy (ART) for HIV requires strict regimen adherence. Motivational interviewing (MI) can improve ART adherence. MI process studies have rarely focussed on ART adherence. Such studies may facilitate MI modifications to improve outcomes. This study employed a single group pre and post-test design with 62 adults with HIV (16 female; mean age 40 years). Therapist use of MI-consistent (MICO) methods, MI spirit, and client change and sustain talk were coded from an MI session. Relationships were assessed with ART schedule adherence. MICO methods positively correlated with change and sustain talk and were negatively associated with proportion of change talk. No variables were associated with ART adherence change. Mediation analysis did not support the MI model of change. This may be due to the fact that ART adherence is determined by both motivational and non-motivational factors. It may also be that bidirectional relationships exist between therapist and client speech.

中文翻译：

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HIV感染者抗逆转录病毒药物依从性的动机访谈机制。

HIV 的抗逆转录病毒治疗 (ART) 需要严格遵守治疗方案。动机性访谈 (MI) 可以提高 ART 的依从性。MI过程研究很少关注ART依从性。此类研究可能有助于 MI 修改以改善结果。本研究采用单组测试前和测试后设计，包括 62 名 HIV 感染者（16 名女性；平均年龄 40 岁）。治疗师使用 MI 一致 (MICO) 方法、MI 精神以及客户改变和维持谈话是从 MI 会话中编码的。通过 ART 时间表依从性评估关系。MICO 方法与改变和维持谈话呈正相关，与改变谈话的比例呈负相关。没有变量与 ART 依从性变化相关。中介分析不支持 MI 模型的变化。这可能是因为 ART 依从性是由动机和非动机因素决定的。也可能是治疗师和来访者言语之间存在双向关系。