Nail psoriasis is a chronic condition which causes pain and functional impairment; thus, it restricts the activities of daily living and worsens the quality of life. Different chemotherapeutic options are available for treating nail psoriasis such as systemic, intralesional, and topical therapies. However, current chemotherapy suffers from several limitations and to overcome them, new advancements are being made worldwide. Various reports have been published on current progress in the treatment of nail psoriasis such as clinical efficacy studies of novel antipsoriatic agents and novel formulation strategies for current chemotherapy. There are several novel nail formulations for the treatment of nail disorders, particularly onychomycosis, such as vesicular colloidal structure (liposomes, niosomes, transfersomes, ethosomes, etc.) and nonvesicular colloidal structures (nano-emulgel, nanocapsules, thermosensitive gel, etc.) These formulations can also prove beneficial for the treatment of nail psoriasis, and will be heavily explored in the near future. This review provides a brief introduction to the disease, its pathogenesis, and its treatment modalities. The review also throws light onto progress and future perspectives in nail psoriasis treatment.

中文翻译：

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指甲银屑病治疗：洞察当前进展和未来趋势。

指甲银屑病是一种慢性病，会导致疼痛和功能障碍；因此，它限制了日常生活活动并降低了生活质量。不同的化疗方案可用于治疗指甲银屑病，例如全身、病灶内和局部治疗。然而，目前的化学疗法有几个限制，为了克服这些限制，世界范围内正在取得新的进展。已经发表了各种关于目前治疗指甲银屑病的进展的报告，例如新型抗银屑病药物的临床疗效研究和当前化疗的新型制剂策略。有几种新的指甲制剂可用于治疗指甲疾病，尤其是甲真菌病，例如囊泡胶体结构（脂质体、niosomes、转移体、ethosomes 等）。）和非水泡胶体结构（纳米乳液、纳米胶囊、热敏凝胶等）这些制剂也可以证明对治疗指甲银屑病有益，并将在不久的将来进行大量探索。本综述简要介绍了该疾病、发病机制和治疗方式。该评论还揭示了指甲银屑病治疗的进展和未来前景。