ABSTRACT The aim of this study was to determine the effects of short and long-term RFR exposure on ABR by evaluating lipid peroxidation and antioxidant status in adult rats. Sixty male albino Wistar rats were randomly divided into four groups. S1:1 week sham, S10:10 weeks sham, E1:1 week RFR, E10:10 weeks RFR. Experimental group rats were exposed to RFR 2 h/day, 5 days/week during the test period. Sham rats were kept in the same conditions without RFR. After the experiment, ABRs were recorded from the mastoids of rats using tone burst acoustic stimuli. Biochemical investigations in rat brain and ultrastructural analysis in temporal cortex were performed. ABR wave I latency prolonged in E1-group and shortened in E10-group compared to their shams. TBARS level increased in E1-group, decreased in E10-group, on the contrary, SOD and CAT activities and GSH level decreased in E1-group, increased in E10-group compared to their sham groups. Edema was present in the neuron and astrocyte cytoplasms and astrocyte end-feet in both E1 and E10 groups. Our results suggest that 900 MHz RFR may have negative effects on the auditory system in acute exposure and no adverse effects in chronic exposure without weekends.

中文翻译：

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急性和慢性暴露于 900 MHz 射频辐射对成年大鼠听觉脑干反应的影响

摘要 本研究的目的是通过评估成年大鼠的脂质过氧化和抗氧化状态来确定短期和长期 RFR 暴露对 ABR 的影响。60 只雄性白化 ​​Wistar 大鼠随机分为四组。S1：1 周假，S10：10 周假，E1：1 周 RFR，E10：10 周 RFR。实验组大鼠在试验期间暴露于 RFR 2 h/天，5 天/周。假大鼠在没有 RFR 的情况下保持在相同的条件下。实验结束后，使用音爆声刺激从大鼠的乳突中记录 ABR。进行了大鼠脑的生化研究和颞叶皮层的超微结构分析。与假手术相比，ABR I 波潜伏期在 E1 组中延长，在 E10 组中缩短。E1 组 TBARS 水平升高，E10 组降低，相反，与假手术组相比，E1 组 SOD 和 CAT 活性和 GSH 水平降低，E10 组升高。E1 和 E10 组的神经元和星形胶质细胞的细胞质以及星形胶质细胞的尾足都存在水肿。我们的结果表明，900 MHz RFR 在急性暴露时可能对听觉系统产生负面影响，而在没有周末的慢性暴露中没有不利影响。