Purpose Given the role of auditory perception in voice production, studies have investigated whether impairments in auditory perception may underlie the noted disruptions in speech in Parkinson's disease (PD). Studies of loudness perception in PD show impairments in the perception of self-generated speech, but not external tones. Studies of pitch perception in PD have only examined external tones, but these studies differed in terms of the interstimulus intervals (ISIs) that were used, did not examine the impact of cognition, and report conflicting results. To clarify pitch perception in PD, this work investigated perception of self-generated vocal pitch, controlling for cognition and ISI. Method A total of 30 individuals with and without PD completed (a) hearing threshold testing, (b) the Montreal Cognitive Assessment, and (c) an adaptive just-noticeable-difference paradigm under two separate ISIs (100 ms and 1,000 ms) to assess acuity to self-generated vocal pitch. Results There was no significant difference in acuity between individuals with and without PD. Both groups demonstrated significantly worse acuity for longer compared to shorter ISIs. Montreal Cognitive Assessment scores were not a significant predictor of acuity. Conclusions The results suggest that acuity to self-generated vocal pitch does not differ between individuals with and without PD.

中文翻译：

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对帕金森病患者自生音调变化的敏锐度

目的鉴于听觉感知在发声中的作用，研究人员调查了听觉感知损伤是否可能是帕金森病 (PD) 患者言语障碍的基础。对 PD 响度感知的研究表明，对自身生成的语音的感知存在障碍，但对外部音调的感知没有障碍。PD 音调感知的研究仅检查了外部音调，但这些研究在使用的刺激间间隔 (ISI) 方面有所不同，没有检查认知的影响，并报告了相互矛盾的结果。为了阐明 PD 中的音高感知，这项工作研究了自我生成的音高感知，控制认知和 ISI。 方法共有 30 名患有和未患有帕金森病的人完成了 (a) 听力阈值测试、(b) 蒙特利尔认知评估和 (c) 在两个单独的 ISI（100 毫秒和 1,000 毫秒）下的适应性刚刚显着差异范式进行评估对自生音高的敏锐度。 结果患有和不患有PD的个体之间的敏锐度没有显着差异。与较短的 ISI 相比，两组患者在较长时间内的敏锐度均明显较差。蒙特利尔认知评估分数并不是敏锐度的重要预测指标。 结论结果表明，患有帕金森病和未患帕金森病的个体对自生音调的敏锐度没有差异。