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Angiostrongylus vasorum in a Red Panda (Ailurus fulgens): Clinical Diagnostic Trial and Treatment Protocol.
Acta Parasitologica ( IF 1.5 ) Pub Date : 2020-08-25 , DOI: 10.1007/s11686-020-00271-6
Mara Bagardi 1 , Vanessa Rabbogliatti 1 , Jessica Bassi 1 , Daniela Gioeni 1 , Maurizio Oltolina 2 , Luca Villa 1
Affiliation  

PURPOSE The literature refers that Angiostrongylus vasorum should always be considered in the differential diagnosis of respiratory diseases in captive red panda (Ailurus fulgens) from endemic areas, and the importance of undertaking a careful diagnostic process and timely medical treatment are crucial when the disease is suspected. The authors think that the description of this clinical case can help other colleagues in the deworming, clinical and anesthesiologic management of infected subjects. METHODS A red panda was referred to the Veterinary Teaching Hospital of the University of Milan in Lodi, due to a diagnosis of A. vasorum formulated in May 2015. The diagnosis was made after the detection of both first-stage larvae by Baermann technique and antigens by serological rapid in-clinic assay. In addition, haemochromocytometric and blood chemistry tests, echocardiography and a CT examination were carried out. RESULTS The subject was successfully treated by oral administration of milbemycin oxime and praziquantel (Milbemax, Novartis, Italy), respectively, at the weekly dose of 12.5 mg/subject and 125 mg/subject for three consecutive weeks, alternated with 20 days of suspension. Treatment continued with the same scheme until clinical examination carried out in Lodi in December 2018. CONCLUSION The follow-up of the described clinical case demonstrates how appropriate management of the infection and the subsequent prophylaxis can correctly eliminate the parasite, thus avoiding the spread of the nematode and the onset of severe and lethal lung forms as described in the literature.

中文翻译:

红熊猫中的血管圆线虫(Ailurus fulgens):临床诊断试验和治疗方案。

目的 文献指出,在对来自流行地区的圈养小熊猫 (Ailurus fulgens) 呼吸道疾病的鉴别诊断中,应始终考虑血管管圆线虫,当怀疑该疾病时,进行仔细的诊断过程和及时的医疗至关重要。 . 作者认为,该临床病例的描述可以帮助其他同事对感染对象进行驱虫、临床和麻醉管理。方法 2015年5月,一头小熊猫被转诊至洛迪米兰大学兽医教学医院,诊断为A. vasorum,经Baermann技术检测到第一期幼虫和抗原后确诊通过血清学快速临床检测。此外,进行了血色细胞计数和血液化学检查、超声心动图和 CT 检查。结果 该受试者通过口服米尔倍霉素肟和吡喹酮(Milbemax,Novartis,Italy)成功治疗,每周剂量为 12.5 mg/受试者和 125 mg/受试者,连续三周,交替停药 20 天。继续使用相同方案进行治疗,直到 2018 年 12 月在洛迪进行临床检查。 结论 所描述的临床病例的随访表明,适当的感染管理和随后的预防可以正确消除寄生虫,从而避免传播线虫和严重和致命的肺形式的发作,如文献中所述。结果 该受试者通过口服米尔倍霉素肟和吡喹酮(Milbemax,Novartis,Italy)成功治疗,每周剂量为 12.5 mg/受试者和 125 mg/受试者,连续三周,交替停药 20 天。继续使用相同方案进行治疗,直到 2018 年 12 月在洛迪进行临床检查。 结论 所描述的临床病例的随访表明,适当的感染管理和随后的预防可以正确消除寄生虫,从而避免传播线虫和严重和致命的肺形式的发作,如文献中所述。结果 该受试者通过口服米尔倍霉素肟和吡喹酮(Milbemax,Novartis,Italy)成功治疗,每周剂量为 12.5 mg/受试者和 125 mg/受试者,连续三周,交替停药 20 天。继续使用相同方案进行治疗,直到 2018 年 12 月在洛迪进行临床检查。 结论 所描述的临床病例的随访表明,适当的感染管理和随后的预防可以正确消除寄生虫,从而避免传播线虫和严重和致命的肺形式的发作,如文献中所述。5 毫克/受试者和 125 毫克/受试者连续三周,交替暂停 20 天。继续使用相同方案进行治疗,直到 2018 年 12 月在洛迪进行临床检查。 结论 所描述的临床病例的随访表明,适当的感染管理和随后的预防可以正确消除寄生虫,从而避免传播线虫和严重和致命的肺形式的发作,如文献中所述。5 毫克/受试者和 125 毫克/受试者连续三周,交替暂停 20 天。继续使用相同方案进行治疗,直到 2018 年 12 月在洛迪进行临床检查。 结论 所描述的临床病例的随访表明,适当的感染管理和随后的预防可以正确消除寄生虫,从而避免传播线虫和严重和致命的肺形式的发作,如文献中所述。
更新日期:2020-08-25
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