Pre-exposure prophylaxis (PrEP) presents an opportunity to expand prevention options for women at risk for HIV infection. Yet, women’s PrEP use remains low and relatively little is known about PrEP acceptability and attitudes among a sub-population of women at risk for HIV—those experiencing intimate partner violence (IPV). A cross-sectional survey included closed and open-ended questions to assess IPV, PrEP acceptability, and attitudes about PrEP use among women seeking care at an urban family planning clinic in Pittsburgh, Pennsylvania (N = 145). Approximately 70% of women reported being willing to use PrEP with the key reasons for potential use including previous STI diagnosis, inconsistent condom use, and lack of or dishonest conversations with partners. Among women reporting recent IPV (41%), potential barriers to PrEP included concerns around drug effects, access/affordability, and adherence. Over half of women reporting recent IPV reported concerns around partner reaction impacting potential PrEP use. Results from this mixed-methods study highlight the need for a woman-centered PrEP intervention that uniquely includes awareness raising and understanding of PrEP for women, as well as reflects the context of IPV in decision-making and care.

暴露前预防（PrEP）为扩大感染HIV风险妇女的预防选择提供了机会。但是，女性的PrEP使用率仍然很低，并且对于处于感染HIV风险的亚人群中遭受亲密伴侣暴力（IPV）的女性，PrEP的可接受性和态度知之甚少。横断面调查包括封闭和开放式的问题，以评估IPV，PrEP的可接受性，以及有关在其中位于宾夕法尼亚州匹兹堡的城市计划生育诊所求医的妇女PrEP的使用态度（ñ = 145）。大约70％的女性表示愿意使用PrEP，其潜在用途的关键原因包括以前的性传播感染诊断，安全套使用不一致以及与伴侣之间的交谈不诚实或不诚实。在报告近期IPV的女性中（41％），PrEP的潜在障碍包括对药物作用，获得/负担能力和依从性的担忧。报告最近IPV的女性中，超过一半的女性表示担心伴侣的反应会影响PrEP的潜在使用。这项混合方法研究的结果表明，需要以妇女为中心的PrEP干预措施，该干预措施独特地包括提高对妇女的PrEP的认识和了解，并反映IPV在决策和护理中的背景。