We performed an in-depth computational image analysis of the baseplate-tail complex of the M4 vibriophage and identified seven major densities in its baseplate, which notably share structural similarities with baseplate modules of a number of other bacteriophages belonging to different species. Employing computational analysis, we explained the helical organization of the sheath protein, wrapping the tail tube. Based on the results obtained in this work along with the proteomics information published previously, we are able to decipher the plausible roles assigned to the different components of the M4 baseplate during infection of the host.

中文翻译：

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O1 ElTor噬菌体M4的底板-尾部复合体的计算图像分析。

我们对M4噬菌体的底板-尾部复合体进行了深入的计算图像分析，并确定了其底板中的七个主要密度，特别是与属于不同物种的许多其他噬菌体的底板模块具有相似的结构。通过计算分析，我们解释了包裹尾管的鞘蛋白的螺旋结构。根据这项工作中获得的结果以及先前发布的蛋白质组学信息，我们能够破译在宿主感染期间分配给M4底板不同组件的合理角色。