Background: The deterioration of cognitive and motor functions and activities of daily living is common in Alzheimer's dementia.

Objectives: The purpose of this study was to investigate the correlation and the strength of the relationship between cognitive function and motor function and activities of daily living after a diagnosis of Alzheimer's disease dementia.

Methods: Sixty-three patients with mild to moderate Alzheimer's disease dementia in a community setting of South Korea were examined for cognitive and motor functions, and functional levels. The test or measures used for cognitive function were the Mini-Mental State Examination (MMSE), Global Deterioration Scale (GDS), and Clinical Dementia Rating (CDR). The 10-meter walking test (10MWT), Berg Balance Scale (BBS), and Timed Up and Go Test (TUG) were used to examine motor function, while the Modified Barthel Index (MBI) and Katz Index (KI) were used to examining activities of daily living.

Results: The MMSE had a positive correlation with that from the BBS (r=.338, p<.05), MBI (r=.363, p<.05), and KI (r=.276, p<.05). The GDS was negatively correlated with BBS (r=.319, p<.05). Multivariate regression analysis showed that MMSE was a major explanatory variable for BBS (R2 =.115, β=.338, p<.05) MBI (R2 =.131, β=.363, p<.05), and KI (R2 =.076, β=.276, p<.05).

Conclusion: The results of the present study show that cognitive function by MMSE is correlated with balance by BBS and activities of daily living by MBI and KI, and MMSE, which are tests or measures for cognitive function, can be explanatory variable to explain variations in the BBS, MBI, and KI in the persons with mild to moderate Alzheimer’s dementia. It may mean that a decrease in cognitive function was found to affect motor function and activities of daily living. Based on this study, appropriate intervention approaches including physical exercise, should be considered for caring for persons with mild to moderate Alzheimer’s dementia in a community setting.

背景：认知和运动功能以及日常生活活动的恶化在阿尔茨海默病中很常见。

目的：本研究的目的是调查阿尔茨海默病痴呆诊断后认知功能与运动功能和日常生活活动之间的相关性和关系强度。

方法：对韩国社区环境中的 63 名轻度至中度阿尔茨海默病痴呆患者进行认知和运动功能以及功能水平的检查。用于认知功能的测试或测量是简易精神状态检查 (MMSE)、总体恶化量表 (GDS) 和临床痴呆评分 (CDR)。10 米步行测试 (10MWT)、伯格平衡量表 (BBS) 和计时起身测试 (TUG) 用于检查运动功能，而改良 Barthel 指数 (MBI) 和 Katz 指数 (KI) 用于检查运动功能。检查日常生活活动。

结果：MMSE 与 BBS (r=.338, p<.05)、MBI (r=.363, p<.05) 和 KI (r=.276, p<.05) 呈正相关）。GDS 与 BBS 呈负相关（r=.319，p<.05）。多元回归分析表明，MMSE 是 BBS (R2 =.115, β=.338, p<.05) MBI (R2 =.131, β=.363, p<.05) 和 KI ( R2 =.076，β=.276，p<.05）。

结论：本研究的结果表明，MMSE 的认知功能与 BBS 的平衡以及 MBI 和 KI 的日常生活活动相关，作为认知功能测试或量度的 MMSE 可以作为解释变量来解释轻度至中度阿尔茨海默病患者的 BBS、MBI 和 KI。这可能意味着发现认知功能下降会影响运动功能和日常生活活动。根据这项研究，应该考虑适当的干预方法，包括体育锻炼，以在社区环境中照顾轻度至中度阿尔茨海默氏症患者。