Many glove manufacturers of chemical protective clothing produce chemical resistance guides to aid in selection of an appropriate product. Some manufacturers provide permeation data, but others provide a general rating system without reporting testing their own products. A critical issue is that considerable variation in chemical resistance, both with breakthrough times and steady-state permeation rates, have been observed with disposable nitrile gloves. The main purpose of this study was to determine whether significant variation in chemical resistance was present between products from a single brand that provided a generalized chemical resistant guide. The objective was to determine if the ratings noted on the chemical resistance guide were sufficient for protection against chemical permeation. The chemical permeation of ten disposable nitrile gloves against three organic solvents of varying polarity (cyclohexane, tert-butanol, and cyclohexanol) was performed in triplicate. Despite the similar chemical resistant ratings for the products, significant variation in both breakthrough times and steady-state permeation rates were observed among the ten nitrile gloves. The largest variation in breakthrough time was about 8-fold. The largest variation in steady-state permeation rate was about 177-fold. A proposed chemical resistance rating system was used to further evaluate the variation in performance, as it would relate to similar rating systems used by glove manufacturers or brands. Polarity played a role in the observed performance, with the nitrile gloves providing increased protection with an increase in solvent polarity, more notably with the dielectric constant. Using a proposed rating system, the percentages of products rating as excellent to good were 20% (cyclohexane), 60% (tert-butanol), and 90% (cyclohexanol). Ultimately, the ratings noted on the general chemical resistance guide were not sufficient for worker protection against chemical permeation. It is not valid to assume that little variation should exist among the different glove products under a same brand or based on the use of generic chemical resistant data. When critical, occupational health and safety professionals should base glove selection on product-specific chemical permeation data.

中文翻译：

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暴露在不同极性的挥发性有机化合物中的类似一次性丁腈手套的化学渗透性：第1部分：产品变化。

许多化学防护服的手套制造商都会提供化学抗性指南，以帮助选择合适的产品。一些制造商提供渗透数据，但其他制造商提供常规评估系统，而无需报告对其自己的产品进行测试。一个关键问题是，一次性丁腈手套已观察到耐化学性的显着变化，包括突破时间和稳态渗透率。这项研究的主要目的是确定提供通用耐化学性指南的单一品牌产品之间的耐化学性是否存在显着差异。目的是确定耐化学性指南上注明的额定值是否足以防止化学渗透。一式三份地进行十个一次性丁腈手套对三种极性不同的有机溶剂（环己烷，叔丁醇和环己醇）的化学渗透。尽管该产品具有相似的耐化学腐蚀等级，但在十只丁腈手套中观察到了突破时间和稳态渗透率的显着变化。突破时间的最大变化约为8倍。稳态渗透率的最大变化约为177倍。提议的耐化学腐蚀等级系统用于进一步评估性能变化，因为它与手套制造商或品牌使用的类似等级系统有关。极性在观察到的性能中起作用，丁腈手套提供了增强的保护，同时增加了溶剂极性，尤其是介电常数。使用提议的评级系统，产品评级为优至良的百分比为20％（环己烷），60％（叔丁醇）和90％（环己醇）。最终，通用耐化学性指南中提到的等级不足以保护工人免受化学渗透。不能假设同一品牌下或基于通用耐化学性数据的不同手套产品之间应几乎没有差异。在紧急情况下，职业健康和安全专业人员应根据产品特定的化学渗透数据选择手套。一般耐化学性指南中提到的等级不足以保护工人免受化学渗透。不能假设同一品牌下或基于通用耐化学性数据的不同手套产品之间应几乎没有差异。在紧急情况下，职业健康和安全专业人员应根据产品特定的化学渗透数据选择手套。一般耐化学性指南中指出的等级不足以保护工人免受化学渗透。不能假设同一品牌下或基于通用耐化学性数据的不同手套产品之间应几乎没有差异。在紧急情况下，职业健康和安全专业人员应根据产品特定的化学渗透数据选择手套。