Bio-inspired wettability patterns for biomedical applications,Materials Horizons

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Bio-inspired wettability patterns for biomedical applications
Materials Horizons ( IF 12.2 ) Pub Date : 2020-09-10 , DOI: 10.1039/d0mh01293a
Junjie Chi ₁ , Xiaoxuan Zhang , Yuetong Wang , Changmin Shao , Luoran Shang , Yuanjin Zhao

Affiliation

Benefiting from the remarkable wettability heterogeneity, bio-inspired wettability patterns present a progressive and versatile platform for manipulating and patterning liquids, which provides an emerging strategy for operating liquid samples with crucial values in biomedical applications. In this review, we present a general summary of bio-inspired wettability patterns. After a compendious introduction of natural wettability phenomena and their underlying mechanisms, we summarize the general design principles and fabrication methods for preparing artificial wettability materials. Next, we shift to patterned surface wettability with an emphasis on the fabrication approaches. Then, we discuss in detail the various practical applications of wettability patterns in the biomedical field, including cell culture, drug screening and biosensors. Critical thinking about the current challenges and future outlook is also provided. We believe that this review would propel the prosperous development of bio-inspired wettability patterns to flourish in the field of biomedical engineering.

中文翻译：

用于生物医学应用的仿生润湿性模式

受益于显着的润湿性异质性，仿生润湿性模式为操作和图案化液体提供了一个先进的多功能平台，为在生物医学应用中具有关键价值的液体样品提供了一种新兴的操作策略。在这篇综述中，我们对仿生润湿性模式进行了一般性总结。在简要介绍了自然润湿现象及其潜在机制之后，我们总结了制备人工润湿材料的一般设计原则和制造方法。接下来，我们转向图案化表面润湿性，重点是制造方法。然后，我们详细讨论了润湿性模式在生物医学领域的各种实际应用，包括细胞培养、药物筛选和生物传感器。还提供了对当前挑战和未来前景的批判性思考。我们相信，这篇综述将推动仿生润湿性模式在生物医学工程领域的蓬勃发展。

更新日期：2020-09-10

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