One of the most disabling nonmotor symptoms in persons with Parkinson’s disease is fatigue, which can decrease the quality of life by restricting the function and activities of daily living (ADL). Nonetheless, sufficient evidence for treating fatigue, including drug or nondrug treatment, is not available. In this study, we evaluated the probable effects of vestibular rehabilitation on fatigue and ADL in patients with Parkinson’s disease. Methods. This was a single-blind clinical trial study in which patients with Parkinson’s disease voluntarily participated based on the inclusion and exclusion criteria. The patients were randomly assigned to the case and control groups. The case group received 24 sessions of vestibular rehabilitation protocol, and conventional rehabilitation was performed in the control group (i.e., 3 sessions each week, each lasted about 60 minutes). Both groups were also given fatigue management advice. Fatigue was measured by the Parkinson Fatigue Scale (PFS) and the Modified Fatigue Impact Scale (MFIS). ADL was measured by the Functional Independence Measure (FIM). All changes were measured from the baseline at the completion of the intervention. Results. Both fatigue () and ADL () improved significantly more in the vestibular intervention group than in the control one. Conclusion. Vestibular rehabilitation may improve fatigue and ADL and therefore can be used as an effective intervention for patients with Parkinson’s disease, which was also found to be well tolerated.

中文翻译：

---

前庭康复对帕金森病患者疲劳和日常生活活动的影响：一项随机对照试验研究。


帕金森病患者最严重的非运动症状之一是疲劳，它会限制日常生活功能和活动 (ADL)，从而降低生活质量。尽管如此，还没有足够的证据来治疗疲劳，包括药物或非药物治疗。在这项研究中，我们评估了前庭康复对帕金森病患者的疲劳和日常生活能力的可能影响。方法。这是一项单盲临床试验研究，帕金森病患者根据纳入和排除标准自愿参与。将患者随机分配到病例组和对照组。病例组接受24次前庭康复方案，对照组进行常规康复（即每周3次，每次持续约60分钟）。两组都获得了疲劳管理建议。疲劳通过帕金森疲劳量表（PFS）和改良疲劳影响量表（MFIS）来测量。 ADL 通过功能独立性测量 (FIM) 来测量。所有变化都是从干预完成时的基线开始测量的。结果。 既疲劳（ )和 ADL ( ）与对照组相比，前庭干预组的改善显着更多。结论。前庭康复可以改善疲劳和日常生活活动能力，因此可以作为帕金森病患者的有效干预措施，而且帕金森病也具有良好的耐受性。