Plant materials play a very significant role as components of products being used both for medicinal and cosmetic purposes. Due to the high content of active substances, they can play an important role as extracts with antioxidant, regenerative, and antiaging properties. The skin aging process depends on various pathological and physiological processes, among which the degradation of extracellular matrix biomolecules such as collagen and elastin, which significantly affect the maintenance of good skin condition, is very important. The secondary metabolites and plant extracts may have collagenase and elastase inhibitory activity. This activity is mainly due to the high content of a wide range of various biologically active compounds, such as polyphenols, which include, among others, flavonoids, phenolic acids, tocopherols, and tannins. The work involved a comprehensive assessment of the plant from Apiaceae family such as Meum athamanticum L., Centella asiatica L., and Aegopodium podagraria L. extract as a multifunctional raw material. During study antioxidant properties, phenolic compounds and flavonoids content, effect on collagenase and elastase enzyme activity (antiaging effect), cytotoxic properties on skin cells (keratinocytes and fibroblasts), and cell migration capacity were analyzed. It has been shown that the highest antioxidant capacity can be observed for the extract of herb of Aegopodium podagraria L. When the concentration reached 5% all tested extracts had a positive effect on the cell proliferation of both keratinocytes and fibroblasts. It turned out that the most promising inhibitor of collagenase and elastase enzymes was the extract from Aegopodium podagraria, which inhibits the activity of both enzymes by over 70% in the concentration of 5% positively affecting the condition of skin cells.

中文翻译：

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伞形科植物的抗衰老和保护特性的比较。

植物材料作为医药和化妆品产品的成分发挥着非常重要的作用。由于活性物质含量高，它们作为具有抗氧化、再生和抗衰老特性的提取物可以发挥重要作用。皮肤衰老过程取决于各种病理和生理过程，其中胶原蛋白和弹性蛋白等细胞外基质生物分子的降解非常重要，它显着影响良好皮肤状态的维持。次生代谢物和植物提取物可能具有胶原酶和弹性蛋白酶抑制活性。这种活性主要是由于多种生物活性化合物的高含量，例如多酚，其中包括黄酮类、酚酸、生育酚和单宁酸等。该工作对伞形科植物Meum athamanticum L.、Centella asiatica L.、Aegopodium podagraria L.提取物作为多功能原料进行了综合评估。在研究过程中，分析了抗氧化特性、酚类化合物和类黄酮含量、对胶原酶和弹性蛋白酶活性的影响（抗衰老作用）、对皮肤细胞（角质形成细胞和成纤维细胞）的细胞毒性特性以及细胞迁移能力。研究表明，Aegopodium podagraria L草本提取物具有最高的抗氧化能力。当浓度达到 5% 时，所有测试的提取物都对角质形成细胞和成纤维细胞的细胞增殖产生积极影响。事实证明，最有前途的胶原酶和弹性蛋白酶抑制剂是Aegopodium podagraria的提取物，它在 5% 的浓度下可抑制两种酶的活性超过 70%，对皮肤细胞的状况产生积极影响。