Non-peripherally tetradodecyloxy substituted copper (CuPc 3) and nickel (NiPc 4) phthalocyanines and the compounds were synthesized. The absorption spectra of synthesized Pcs were showed monomeric behavior evidenced by a narrow between 680 and 750 nm (Q band) for CuPc(3) and NiPc(4) in different solvents. The fluorescence behavior of the Pcs was studied in chloroform. The CuPc (3) showed outstanding stability in THF as solvent during photodegradation studies. The possible photodynamic therapy reaction mechanisms were studied through the calculation of ionization potentials and electron affinity in both vacuum and solvents using SCRF model.

合成了非外围的四十二烷氧基取代的铜（CuPc 3）和镍（NiPc 4）酞菁类化合物。合成的Pcs的吸收光谱显示出单体行为，在不同溶剂中CuPc（3）和NiPc（4）在680至750 nm（Q谱带）之间较窄。在氯仿中研究了Pcs的荧光行为。在光降解研究过程中，CuPc（3）在THF中作为溶剂显示出出色的稳定性。通过使用SCRF模型计算真空和溶剂中的电离势和电子亲和力，研究了可能的光动力疗法反应机理。