A Perspective on Synthesis and Applications of Fluorenones,ChemistrySelect

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A Perspective on Synthesis and Applications of Fluorenones
ChemistrySelect ( IF 1.9 ) Pub Date : 2020-09-10 , DOI: 10.1002/slct.202002695
Sagarkumar Patel ₁ , Bhagyashri Rathod ₁ , Siddulu Regu ₁ , Shivam Chak ₁ , Amit Shard ₁

Affiliation

Fluorenones are important constituents in material, medical and chemical sciences with potential applications in various domains. The key factors responsible for the diverse usage of fluorenones in material sciences are their intriguing and tunable photo, as well as physico‐chemical properties. Besides this, the presence of conjugated poly‐(en)ynes in the fluorenones makes them molecules of interest in material sciences. Fluorenones show various biological activities like antibiotics, anticancer, antiviral, and neuromodulatory, etc. Organic chemists are developing various protocols for the synthesis of fluorenones. Despite several protocols developed for their synthesis since 1931, there is no review covering their entire synthetic protocols. This review includes several classical and novel synthetic approaches for the synthesis of fluorenones. Furthermore, we delineated the mechanism by which they have been synthesized.

中文翻译：

芴酮的合成及应用前景

芴酮是材料，医学和化学科学中的重要组成部分，在各个领域都有潜在的应用。材料科学中芴酮的多样化使用的关键因素是其有趣的和可调谐的光以及理化性质。除此之外，芴酮中共轭聚炔的存在使它们成为材料科学中令人关注的分子。芴酮具有多种生物活性，如抗生素，抗癌剂，抗病毒剂和神经调节剂等。有机化学家正在开发各种方法来合成芴酮。尽管自1931年以来已开发出几种用于合成的方案，但尚无关于其整个合成方案的综述。这项审查包括几种经典的和新颖的合成方法，芴酮。

更新日期：2020-09-10

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