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Application of Carbon Nanomaterials in Human Virus Detection
Journal of Science: Advanced Materials and Devices ( IF 7.382 ) Pub Date : 2020-12-01 , DOI: 10.1016/j.jsamd.2020.09.005
Hamide Ehtesabi

Human-pathogenic viruses are still a chief reason for illness and death on the globe, as epitomized by the COVID-19 pandemic instigated by a coronavirus in 2020. Multiple novel sensors have been invented because diseases must be detected and diagnosed as early as possible, and recognition methods have to be carried out with minimal invasivity. Sensors have been particularly developed focusing on miniaturization by the use of nanomaterials for fabricating nanosensors. The nano-sized nature of nanomaterials and their exclusive optical, electronical, magnetical, and mechanical attributes can enhance patient care through the use of sensors with minimal invasivity and extreme sensitivity. Amongst the nanomaterials utilized for fabricating nano-sensors, carbon-based nanomaterials are promising as these sensors respond better to signals in various sensing settings. This review provides an overview of the recent developments in carbon nanomaterial-based biosensors for viral recognition based on the biomarkers that arise from the infection, the nucleic acids from the viruses, and the entire virus. The role of carbon nanomaterials is highlighted by the improvement of sensor and recognition functionality. The Dengue virus, Ebola virus, Hepatits virus, human immunodeficiency virus (HIV), influenza virus, Zika virus and Adenovirus are the virus types reviewed to illustrate the implementation of the techniques. Finally, the drawbacks and advantages of carbon nanomaterial-based biosensors for viral recognition are identified and discussed.

中文翻译:

碳纳米材料在人类病毒检测中的应用

人类致病病毒仍然是全球疾病和死亡的主要原因,2020 年由冠状病毒引发的 COVID-19 大流行就是一个缩影。由于必须尽早检测和诊断疾病,已经发明了多种新型传感器,和识别方法必须以最小的侵入性进行。通过使用纳米材料制造纳米传感器,传感器的开发特别侧重于小型化。纳米材料的纳米级性质及其独特的光学、电子、磁性和机械属性可以通过使用具有最小侵入性和极高灵敏度的传感器来增强患者护理。在用于制造纳米传感器的纳米材料中,碳基纳米材料很有前景,因为这些传感器可以更好地响应各种传感设置中的信号。本综述概述了基于碳纳米材料的生物传感器用于病毒识别的最新进展,该传感器基于感染产生的生物标志物、病毒核酸和整个病毒。传感器和识别功能的改进突出了碳纳米材料的作用。登革热病毒、埃博拉病毒、肝炎病毒、人类免疫缺陷病毒 (HIV)、流感病毒、寨卡病毒和腺病毒是经过审查的病毒类型,以说明这些技术的实施。最后,确定并讨论了基于碳纳米材料的生物传感器用于病毒识别的缺点和优点。本综述概述了基于碳纳米材料的生物传感器用于病毒识别的最新进展,该传感器基于感染产生的生物标志物、病毒核酸和整个病毒。传感器和识别功能的改进突出了碳纳米材料的作用。登革热病毒、埃博拉病毒、肝炎病毒、人类免疫缺陷病毒 (HIV)、流感病毒、寨卡病毒和腺病毒是经过审查的病毒类型,以说明这些技术的实施。最后,确定并讨论了基于碳纳米材料的生物传感器用于病毒识别的缺点和优点。本综述概述了基于碳纳米材料的生物传感器用于病毒识别的最新进展,该传感器基于感染产生的生物标志物、病毒核酸和整个病毒。传感器和识别功能的改进突出了碳纳米材料的作用。登革热病毒、埃博拉病毒、肝炎病毒、人类免疫缺陷病毒 (HIV)、流感病毒、寨卡病毒和腺病毒是经过审查的病毒类型,以说明这些技术的实施。最后,确定并讨论了基于碳纳米材料的生物传感器用于病毒识别的缺点和优点。和整个病毒。传感器和识别功能的改进突出了碳纳米材料的作用。登革热病毒、埃博拉病毒、肝炎病毒、人类免疫缺陷病毒 (HIV)、流感病毒、寨卡病毒和腺病毒是被审查的病毒类型,以说明这些技术的实施。最后,确定并讨论了基于碳纳米材料的生物传感器用于病毒识别的缺点和优点。和整个病毒。传感器和识别功能的改进突出了碳纳米材料的作用。登革热病毒、埃博拉病毒、肝炎病毒、人类免疫缺陷病毒 (HIV)、流感病毒、寨卡病毒和腺病毒是经过审查的病毒类型,以说明这些技术的实施。最后,确定并讨论了基于碳纳米材料的生物传感器用于病毒识别的缺点和优点。
更新日期:2020-12-01
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