Abstract

The transformation of N-substituted 2-heteroylthiosemicarbazides to N-(2-substituted imino)-4-amino-5-cyanothiazol-3(2H)-3-yl)-heteroyl-2-carboxamides was achieved via the reaction with tetracyanoethylene, which is used as a building block in this transformation. The structures of the products have been confirmed unambiguously by single-crystal X-ray structure analysis. A rationale for the formation of the products is presented.

Graphic abstract

中文翻译：

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四甲基氨基乙烯是轻松合成杂基四取代噻唑的基础

摘要

通过与四氰基乙烯反应，实现了N-取代的2-杂基硫代氨基脲向N-（2-取代的亚氨基）-4-氨基-5-氰基噻唑-3 （2 H）-3-基）-杂基-2-羧酰胺的转化。 ，它在此转换中用作构建块。通过单晶X射线结构分析已明确确认了产物的结构。提出了形成产品的基本原理。

图形摘要