Chronic subdural hematoma is a common neurosurgical pathology, which is more commonly seen in the elderly age group. Few patients with chronic subdural hematoma (cSDH) can have seizures—either before or after surgical intervention. Reported incidence of seizures varies from 0.7–18.5% in patients with cSDH. Many factors which have been proposed to increase the risk of seizures in these patients include the presence of encapsulated membranes, occult cortical injury, mass effect, or an acute hemorrhage. The role of prophylactic antiepileptic drugs is not very clear in cSDH. We reviewed the currently available evidence for the use of prophylactic antiepileptic drugs (AEDs) in patients with cSDH. We included 13 studies in the systematic review and 6 studies compared the incidence of seizures in patients who received antiepileptic drugs with those who did not. Our review did not find any significant reduction in the incidence of seizures in patients with cSDH following administration of antiepileptic drugs.

慢性硬膜下血肿是一种常见的神经外科病理，多见于老年人群。很少有慢性硬膜下血肿 (cSDH) 患者会在手术干预之前或之后出现癫痫发作。据报道，cSDH 患者的癫痫发作发生率从 0.7% 到 18.5% 不等。许多被提议增加这些患者癫痫发作风险的因素包括包膜的存在、隐匿性皮质损伤、占位效应或急性出血。预防性抗癫痫药物在 cSDH 中的作用不是很清楚。我们回顾了在 cSDH 患者中使用预防性抗癫痫药物 (AED) 的当前可用证据。我们在系统评价中纳入了 13 项研究，6 项研究比较了接受抗癫痫药物治疗的患者与未接受抗癫痫药物治疗的患者的癫痫发作发生率。我们的审查未发现 cSDH 患者服用抗癫痫药物后癫痫发作的发生率有任何显着降低。