The recent emergence of the novel coronavirus (CoV) or severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses a global threat to human health and economy. As of June 26, 2020, over 9.4 million cases of infection, including 482,730 deaths, had been confirmed across 216 countries. To combat a devastating virus pandemic, numerous studies on vaccine development are urgently being accelerated. In this review article, we take a brief look at the characteristics of SARS-CoV-2 in comparison to SARS and Middle East respiratory syndrome (MERS)-CoVs and discuss recent approaches to coronavirus disease-2019 (COVID-19) vaccine development.

中文翻译：

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新出现的人类冠状病毒：SARS、MERS 和 COVID-19 的动物模型和疫苗研究


最近出现的新型冠状病毒（CoV）或严重急性呼吸综合征冠状病毒-2（SARS-CoV-2）对人类健康和经济构成全球威胁。截至2020年6月26日，216个国家已确诊超过940万例感染病例，其中482,730人死亡。为了对抗毁灭性的病毒大流行，许多有关疫苗开发的研究正在紧急加速。在这篇综述文章中，我们简要介绍了 SARS-CoV-2 与 SARS 和中东呼吸综合征 (MERS)-CoV 相比的特征，并讨论了 2019 年冠状病毒病 (COVID-19) 疫苗开发的最新方法。