This paper presents the design of a bioinspired synaptic integrated circuit, which takes into account the interactions of astrocyte in a tripartite synapse. These interactions result in activation of Ca²⁺ ion waves through fast and slow activation pathways which affect the synapse and postsynaptic neuron. The circuit has been implemented in TSMC 65-nm CMOS technology with 1.2 V supply voltage. Dynamic and nonlinear characteristics of the interactions have been implemented based on nonlinear characteristics of field effect transistors and few external capacitors. This design used few components from previous works, including ML neuron and Ca²⁺ circuit. All components are scaled to 65 nm and implemented in weak inversion operating region. Simulation results confirm that the proposed circuit demonstrates the functionality of physical model with acceptable relative mean square error and low power consumption of about 37 nW. The effects of supply voltage sensitivity, variability of threshold voltage and noise on the Ca²⁺ circuit have been studied. Circuit layout for main components including presynaptic neuron, postsynaptic neuron and the synapse has been prepared, with the area of 80 µm². Post-layout simulation of the neuron with parasitics demonstrates the feasibility of the proposed model for fabrication. This circuit structure can be used for the study and demonstration of various functionalities associated with astrocyte including self-repair.

中文翻译：

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采用65 nm CMOS技术的生物启发的三方突触模拟集成电路的设计

本文介绍了一种生物启发的突触集成电路的设计，该电路考虑了三方突触中星形胶质细胞的相互作用。这些相互作用导致Ca ²⁺离子波通过影响突触和突触后神经元的快速和慢速活化途径活化。该电路已采用台积电65纳米CMOS技术实现，电源电压为1.2V。基于场效应晶体管的非线性特性和很少的外部电容器，实现了相互作用的动态和非线性特性。该设计使用了以前工作中的少量成分，包括ML神经元和Ca ²⁺电路。所有组件均按比例缩放至65 nm，并在弱反转工作区域内实现。仿真结果证实，所提出的电路以可接受的相对均方误差和约37 nW的低功耗演示了物理模型的功能。研究了电源电压灵敏度，阈值电压变化和噪声对Ca ²⁺电路的影响。已经准备了包括突触前神经元，突触后神经元和突触在内的主要组件的电路布局，面积为80 µm ²。具有寄生效应的神经元的布局后仿真证明了所提出的模型用于制造的可行性。该电路结构可用于研究和证明与星形胶质细胞相关的各种功能，包括自我修复。