In many clinical applications it is relevant to observe dynamic changes in oxygenation. Therefore the ability of dynamic imaging with time domain (TD) near-infrared optical tomography (NIROT) will be important. But fast imaging is a challenge. The data acquisition of our handheld TD NIROT system based on single photon avalanche diode (SPAD) camera and 11 light sources was consequently accelerated. We tested the system on a diffusive medium simulating tissue with a moving object embedded. With 3D image reconstruction, the moving object was correctly located using only 0.2 s exposure time per source.

中文翻译：

---

基于SPAD相机的动态时域近红外光学层析成像

在许多临床应用中，观察氧合作用的动态变化很重要。因此，使用时域（TD）近红外光学层析成像（NIROT）进行动态成像的能力将非常重要。但是快速成像是一个挑战。因此，基于单光子雪崩二极管（SPAD）摄像机和11个光源的手持式TD NIROT系统的数据采集得以加速。我们在扩散介质上测试了该系统，该介质模拟了嵌入了移动物体的组织。通过3D图像重建，每个源仅需0.2 s的曝光时间即可正确定位移动物体。