Capillary electrophoresis represents a promising technique in the field of pharmaceutical analysis. The presented review provides a summary of capillary electrophoretic methods suitable for routine quality control analyses of small molecule drugs published since 2015. In total, more than 80 discussed methods are sorted into three main sections according to the applied electroseparation modes (capillary zone electrophoresis, electrokinetic chromatography, and micellar, microemulsion, and liposome‐electrokinetic chromatography) and further subsections according to the applied detection techniques (UV, capacitively coupled contactless conductivity detection, and mass spectrometry). Key parameters of the procedures are summarized in four concise tables. The presented applications cover analyses of active pharmaceutical ingredients and their related substances such as degradation products or enantiomeric impurities. The contribution of reported results to the current knowledge of separation science and general aspects of the practical applications of capillary electrophoretic methods are also discussed.

中文翻译：

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用于药物质量控制分析的毛细管电泳方法：综述。

毛细管电泳是药物分析领域的一项有前途的技术。本综述总结了自 2015 年以来发表的适用于小分子药物常规质量控制分析的毛细管电泳方法。 总共有 80 多种讨论的方法根据应用的电分离模式（毛细管区带电泳、电动色谱、胶束、微乳液和脂质体-电动色谱）以及根据应用的检测技术（UV、电容耦合非接触式电导检测和质谱）进一步细分。程序的关键参数总结在四个简明的表格中。提出的应用程序涵盖活性药物成分及其相关物质的分析，例如降解产物或对映异构体杂质。还讨论了报告结果对当前分离科学知识和毛细管电泳方法实际应用的一般方面的贡献。