Malaria interventions may reduce the burden of clinical malaria disease, the transmission of malaria parasites, or both. As malaria interventions are developed and evaluated, including those interventions primarily targeted at reducing disease, they may also impact parasite transmission. Achieving global malaria eradication will require optimizing the transmission-reducing potential of all available interventions. Herein, we discuss the relationship between malaria parasite transmission and disease, including mechanisms by which disease-targeting interventions might also impact parasite transmission. We then focus on three malaria interventions with strong evidence for reducing the burden of clinical malaria disease and examine their potential for also reducing malaria parasite transmission.

疟疾干预措施可以减轻临床疟疾疾病的负担和/或疟疾寄生虫的传播。随着疟疾干预措施的制定和评估，包括那些主要旨在减少疾病的干预措施，它们也可能影响寄生虫传播。实现全球消灭疟疾需要优化所有可用干预措施的减少传播潜力。在此，我们讨论疟疾寄生虫传播与疾病之间的关系，包括针对疾病的干预措施也可能影响寄生虫传播的机制。然后，我们重点关注三种疟疾干预措施，有强有力的证据表明可以减轻临床疟疾疾病的负担，并研究它们减少疟疾寄生虫传播的潜力。