Herein, a new modified pencil graphite electrode (PGE) is presented for insulin assessing and quantifying. For this approach, Ni-nanoparticles (NiNPs) and methylbenzoate (MB) were decorated on PGE using cyclic voltammetry (CV) technique for producing the PGE/NiNPs/MB platform. The proposed modified electrode fairly responded to insulin and achieved the desirable electro catalytic parameters of α = 0.71, log ks = 3.34, and Γ = 2.22 × 10⁻⁸. The mentioned sensor exhibited a prominent linear behavior between current intensities and concentration values in covering ranges of 25–450 nmolL⁻¹, monitoring by differential pulse voltammetry (DPV) technique. So, this new electrochemical device is promising for insulin content detection in biological media with convincing signals and free from side interferences.

在此，提出了一种新的改进的铅笔状石墨电极（PGE）用于胰岛素评估和定量。对于此方法，使用循环伏安法（CV）技术在PGE上装饰镍纳米颗粒（NiNPs）和苯甲酸甲酯（MB），以生产PGE / NiNPs / MB平台。所提出的修饰电极对胰岛素相当敏感，并达到了理想的电催化参数，α= 0.71，log ks = 3.34，Γ= 2.22×10 ^-8。提到的传感器在25–450 nmolL ^-1的覆盖范围内电流强度和浓度值之间表现出显着的线性行为，通过差分脉冲伏安法（DPV）技术进行监控。因此，这种新的电化学装置有望在具有令人信服的信号且没有侧面干扰的生物介质中检测胰岛素含量。