Urgent treatments, in any modality, to fight SARS-CoV-2 infections are desired by society in general, by health professionals, by Estate-leaders and, mainly, by the scientific community, because one thing is certain amidst the numerous uncertainties regarding COVID-19: knowledge is the means to discover or to produce an effective treatment against this global disease. Scientists from several areas in the world are still committed to this mission, as shown by the accelerated scientific production in the first half of 2020 with over 25,000 published articles related to the new coronavirus. Three great lines of publications related to COVID-19 were identified for building this article: The first refers to knowledge production concerning the virus and pathophysiology of COVID-19; the second regards efforts to produce vaccines against SARS-CoV-2 at a speed without precedent in the history of science; the third comprehends the attempts to find a marketed drug that can be used to treat COVID-19 by drug repurposing. In this review, the drugs that have been repurposed so far are grouped according to their chemical class. Their structures will be presented to provide better understanding of their structural similarities and possible correlations with mechanisms of actions. This can help identifying anti-SARS-CoV-2 promising therapeutic agents.

全社会、卫生专业人员、行业领袖以及主要是科学界都希望采取任何方式的紧急治疗来对抗 SARS-CoV-2 感染，因为在有关新冠病毒的众多不确定性中有一件事是确定的-19：知识是发现或产生针对这一全球性疾病的有效治疗方法的手段。来自世界多个地区的科学家仍然致力于这一使命，2020 年上半年科学产出加速，发表了超过 25,000 篇与新型冠状病毒相关的文章。为构建本文，确定了与 COVID-19 相关的三大出版物：第一个是关于 COVID-19 病毒和病理生理学的知识生产；第二个涉及以科学史上前所未有的速度生产 SARS-CoV-2 疫苗的努力；第三个是尝试通过药物再利用来寻找可用于治疗 COVID-19 的上市药物。在本次审查中，迄今为止已改变用途的药物根据其化学类别进行分组。将介绍它们的结构，以便更好地理解它们的结构相似性以及与作用机制可能的相关性。这有助于识别有前景的抗 SARS-CoV-2 治疗药物。