Abstract

In the past decade a large body of evidence has accumulated on risk factors for dementia, primarily from Europe and North America. Drawing on recent integrative reviews and a consensus workshop, the International Research Network on Dementia Prevention developed a consensus statement on priorities for future research. Significant gaps in geographical location, representativeness, diversity, duration, mechanisms, and research on combinations of risk factors were identified. Future research to inform dementia risk reduction should fill gaps in the evidence base, take a life-course, multi-domain approach, and inform population health approaches that improve the brain-health of whole communities.

中文翻译：

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痴呆症风险降低和预防研究的未来方向：痴呆症预防共识国际研究网络。

 抽象的

在过去的十年中，积累了大量关于痴呆症危险因素的证据，这些证据主要来自欧洲和北美。根据最近的综合审查和共识研讨会，国际痴呆症预防研究网络就未来研究的优先事项制定了共识声明。确定了地理位置、代表性、多样性、持续时间、机制和风险因素组合研究方面的显着差距。未来为降低痴呆症风险提供信息的研究应填补证据基础的空白，采取生命全程、多领域的方法，并为改善整个社区大脑健康的人口健康方法提供信息。