当前位置: X-MOL 学术Chem. Sci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
3-Aminooxetanes: versatile 1,3-amphoteric molecules for intermolecular annulation reactions
Chemical Science ( IF 7.6 ) Pub Date : 2020-09-08 , DOI: 10.1039/d0sc04254d
Zengwei Lai 1, 2 , Renwei Zhang 1 , Qiang Feng 1 , Jianwei Sun 1
Affiliation  

Despite the versatility of amphoteric molecules, stable and easily accessible ones are still limitedly known. As a result, the discovery of new amphoteric reactivity remains highly desirable. Herein we introduce 3-aminooxetanes as a new family of stable and readily available 1,3-amphoteric molecules and systematically demonstrated their amphoteric reactivity toward polarized π-systems in a diverse range of intermolecular [3 + 2] annulations. These reactions not only enrich the reactivity of oxetanes, but also provide convergent access to valuable heterocycles.

中文翻译:


3-氨基氧杂环丁烷:用于分子间成环反应的多功能 1,3- 两性分子



尽管两性分子具有多种用途,但稳定且易于获得的两性分子仍然知之甚少。因此,新的两性反应活性的发现仍然非常令人期待。在此,我们介绍了 3-氨基氧杂环丁烷作为稳定且易于获得的 1,3- 两性分子的新家族,并系统地证明了它们在各种分子间 [3 + 2] 环化中对极化 π 系统的两性反应活性。这些反应不仅丰富了氧杂环丁烷的反应活性,而且还提供了获得有价值的杂环的聚合途径。
更新日期:2020-09-23
down
wechat
bug