Recently, rehabilitative exercise therapies have been described as an important method of overcoming the limitations of the conventional therapies for Parkinson’s disease. The present study aimed to evaluate efficacy and safety of exercise therapies for Parkinson’s disease. Randomized controlled trials that evaluated exercise therapies in patients with Parkinson’s disease until December 2016 were searched for in five electronic databases: PubMed, CENTRAL, EMBASE, OASIS, and CNKI. Eighteen studies (1,144 patients) were included. The overall methodological quality was not high. Patients who underwent exercise therapies exhibited statistically significant improvements in the total UPDRS, UPDRS II and III, Berg Balance Scale, preferred walking speed, and Timed Up and Go Test compared to patients who underwent nonexercise therapies. In comparison to patients who performed regular activity, patients who underwent exercise therapies exhibited statistically significant improvements in the total UPDRS, UPDRS II, and UPDRS III. Exercise therapies were found to be relatively safe. Exercise therapies might promote improvements in the motor symptoms of Parkinson’s disease. However, due to the small number of randomized controlled trials and methodological limitations, we are unable to draw concrete conclusions. Therefore, further studies with better designs will be needed.

中文翻译：

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帕金森病的运动疗法：系统回顾和荟萃分析。

最近，康复运动疗法被认为是克服帕金森病常规疗法局限性的重要方法。本研究旨在评估运动疗法治疗帕金森病的有效性和安全性。在五个电子数据库中检索了截至 2016 年 12 月评估帕金森病患者运动疗法的随机对照试验：PubMed、CENTRAL、EMBASE、OASIS 和 CNKI。纳入了 18 项研究（1,144 名患者）。总体方法学质量不高。与接受非运动治疗的患者相比，接受运动治疗的患者在总 UPDRS、UPDRS II 和 III、Berg 平衡量表、首选步行速度以及计时起行测试方面表现出统计学上显着的改善。与进行定期活动的患者相比，接受运动疗法的患者在总 UPDRS、UPDRS II 和 UPDRS III 方面表现出统计学上显着的改善。研究发现运动疗法相对安全。运动疗法可能会促进帕金森病运动症状的改善。然而，由于随机对照试验数量较少和方法学限制，我们无法得出具体结论。因此，需要进一步研究更好的设计。