Abstract Acetone and n-heptane are widely applied in pharmaceutical industry as benign solvents and are observed in the wastewater. Because acetone and n-hexane can form an azeotropic mixture, it is impossible to recover acetone and n-heptane with high purity from the wastewater using conventional distillation. In this research, for separating the azeotrope (acetone + n-heptane) by homogeneous extractive distillation, 1-chlorobutane and butyl propanoate were chosen as the intermediate and heavy boiling entrainers. The isobaric vapour-liquid equilibrium (VLE) behaviour for the three binary systems (acetone + 1-chlorobutane), (butyl propanoate + acetone) and (n-heptane + butyl propanoate) were reported at 101.3 kPa. The values of the excess Gibbs energy ( G E ) were calculated to explore the nonideal of the systems. The thermodynamic consistency of the determined VLE values was checked by the van Ness and Herington tests. In addition, the determined VLE data were fitted by the UNIQUAC, Wilson, and NRTL models. The parameters of those models were regressed, which are helpful for simulating the separation process with the intermediate and heavy boiling entrainers by extractive distillation.

中文翻译：

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使用中沸点和重沸点夹带剂通过萃取蒸馏分离共沸混合物（丙酮 + 正庚烷）：气液平衡测量和相关性

摘要 丙酮和正庚烷作为良性溶剂广泛应用于制药工业，并在废水中观察到。由于丙酮和正己烷可以形成共沸混合物，因此不可能使用常规蒸馏从废水中回收高纯度的丙酮和正庚烷。在本研究中，为了通过均相萃取精馏分离共沸物（丙酮 + 正庚烷），选择 1-氯丁烷和丙酸丁酯作为中沸点和重沸点夹带剂。三个二元系统（丙酮 + 1-氯丁烷）、（丙酸丁酯 + 丙酮）和（正庚烷 + 丙酸丁酯）的等压汽液平衡 (VLE) 行为报告为 101.3 kPa。计算过量吉布斯能量 (GE) 的值以探索系统的非理想状态。确定的 VLE 值的热力学一致性通过 van Ness 和 Herington 测试进行检查。此外，确定的 VLE 数据由 UNIQUAC、Wilson 和 NRTL 模型拟合。对这些模型的参数进行了回归，这有助于模拟萃取精馏中重沸点夹带剂的分离过程。