After three decades of the amazing progress made on molecular studies of plant–microbe interactions (MPMI), we have begun to ask ourselves “what are the major questions still remaining?” as if the puzzle has only a few pieces missing. Such an exercise has ultimately led to the realization that we still have many more questions than answers. Therefore, it would be an impossible task for us to project a coherent “big picture” of the MPMI field in a single review. Instead, we provide our opinions on where we would like to go in our research as an invitation to the community to join us in this exploration of new MPMI frontiers.

中文翻译：

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植物免疫机制：从还原论到整体观点。

植物与微生物相互作用的分子研究（MPMI）取得了三十年的惊人进展后，我们开始问自己“仍然存在哪些主要问题？”就好像拼图只缺少几块一样。这样的练习最终让我们认识到我们的问题仍然多于答案。因此，我们不可能在一次审查中对 MPMI 领域做出连贯的“全局”。相反，我们就我们的研究方向提出意见，邀请社区加入我们对 MPMI 新前沿的探索。