Two new Zn(II)-based coordination polymers {[Zn₃(L₁)₆(H₂O)]∙(H₂O)₄}_n (1, HL₁ = 4-(tetrazol-5-yl)phenyl-4,2′:6′,4″-terpyridine) and [Zn₂Cl₂(L₂)₂H₂O]_n (2, HL₂ = 4-([2,2′:6’,2″’-terpyridin]-4′-yl)benzoic acid) have been successfully prepared using two similar organic ligands with distinct donor groups under similar reaction conditions. The distinct structural features and donor atoms make the two complexes show different water stability, and the complex 1 with good water stability, which can be utilized as the sensor for Fe³⁺ ion detection in water. The value of Stern–Volmer quenching constant of 1 to the Fe³⁺ is 5.77 × 10⁴ M^− 1, which lies in the top region of the reported CP-based sensors. The mechanism investigation reveals that the energy transfer of resonance from the complex 1 to the Fe³⁺ ion can account for its fluorescent quenching behavior. The treatment activity of compounds 1 and 2 on the postpartum hemorrhage (PPH) was assessed. First, the cytotoxicity of compounds 1 and 2 on human umbilical vein endothelial cells was assessed with Cell Counting Kit-8 detection kit. Then, to evaluate the prevention of compounds 1 and 2 on the PPH, we conducted the Lowry method and detected the clotting factor IX and anticoagulant factor III contents after the indicated treatment. Finally, the inflammatory response in mice was determined by ELISA method, and the IL-6 and IL-8 levels were determined.

两种新的基于Zn（II）的配位聚合物{[Zn ₃（L ₁）₆（H ₂ O）]∙（H ₂ O）₄ } _n（1，HL ₁  = 4-（四唑-5-基）苯基-4,2'：6'，4''-吡啶）和[Zn ₂ Cl ₂（L ₂）₂ H ₂ O] _n（2，HL ₂ 在相似的反应条件下，使用具有不同供体基团的两个相似的有机配体成功地制备了4-（[[2,2'：6'，2'''-三联吡啶] -4'-基）苯甲酸。独特的结构特征和给体原子使两种配合物表现出不同的水稳定性，且配合物1具有良好的水稳定性，可作为水中Fe ³⁺离子检测的传感器。Fe ³⁺的Stern–Volmer猝灭常数为1的数值为5.77×10 ⁴ M ^-1，位于报道的基于CP的传感器的顶部。机理研究表明，共振能量从复合物1转移到Fe ³⁺离子可以解释其荧光猝灭行为。评估了化合物1和2对产后出血（PPH）的治疗活性。首先，使用Cell Counting Kit-8检测试剂盒评估化合物1和2对人脐静脉内皮细胞的细胞毒性。然后，为了评估化合物1和2对PPH的预防作用，我们进行了Lowry方法，并在指定的治疗后检测了凝血因子IX和抗凝血因子III的含量。最后，通过ELISA法确定小鼠的炎症反应，并测定IL-6和IL-8水平。