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Histopathological effect of pterostilbene as chemoprevention in N-nitroso-tri-chloroethylurea (NTCU)-induced lung squamous cell carcinoma (SCC) mouse model.
Histology and Histopathology ( IF 2.5 ) Pub Date : 2020-09-07 , DOI: 10.14670/hh-18-247
Omchit Surien 1 , Ahmad Rohi Ghazali 1 , Siti Fathiah Masre 1
Affiliation  

Lung cancer is the leading cause of cancer-related deaths, and squamous cell carcinoma (SCC) is one of the most common types of lung cancer. Chemoprevention of lung cancer has gained increasing popularity as an alternative to treatment in reducing the burden of lung cancer. Pterostilbene (PS) may be developed as a chemopreventive agent due to its pharmacological activities, such as anti-proliferative, anti-inflammatory and antioxidant properties. This study aimed to investigate the effect of PS on the development of lung SCC in the mouse model.

中文翻译:

紫檀芪在 N-亚硝基三氯乙基脲 (NTCU) 诱导的肺鳞状细胞癌 (SCC) 小鼠模型中作为化学预防的组织病理学作用。

肺癌是癌症相关死亡的主要原因,鳞状细胞癌 (SCC) 是最常见的肺癌类型之一。肺癌的化学预防作为减轻肺癌负担的替代治疗方法越来越受欢迎。由于其药理活性,例如抗增殖、抗炎和抗氧化特性,紫檀 (PS) 可能被开发为化学预防剂。本研究旨在研究 PS 对小鼠模型中肺 SCC 发展的影响。
更新日期:2020-09-09
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