Purpose of review 

The purpose of this review is to describe the contemporary evaluation and management of tall cell variant of papillary thyroid carcinoma with an emphasis on the clinical features.

Recent findings 

Tall cell variant of papillary thyroid carcinoma is the most common aggressive subtype. Within the last few years, the diagnostic criteria for this entity have evolved. Studies have elucidated a better understanding of the clinical implications and pathophysiology of this variant. In this review, the studies presented reflect cumulative and aggregated data from metaanalyses, systematic reviews, and large database investigations utilizing the current diagnostic criteria.

Summary 

Overall, tall cell variant of papillary thyroid carcinoma represents an aggressive subtype of well-differentiated thyroid carcinoma with more prevalent high-risk features and a poorer clinical outcome.

中文翻译：

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甲状腺乳头状癌高细胞变异的当代评价和处理

审查目的 

这篇综述的目的是描述现代乳头状甲状腺癌高细胞变异的评估和治疗，并着重于临床特征。

最近的发现 

甲状腺乳头状癌的高细胞变异是最常见的侵袭性亚型。在最近几年中，该实体的诊断标准已经发展。研究阐明了对该变体的临床意义和病理生理学的更好理解。在本综述中，提出的研究反映了使用当前诊断标准进行的荟萃分析，系统评价和大型数据库研究中的累积和汇总数据。

概要 

总体而言，高细胞型乳头状甲状腺癌代表分化良好的积极的亚型甲状腺癌具有更普遍的高风险特征和较差的临床结果。