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Do we understand the pathophysiology of GERD after sleeve gastrectomy?
Annals of the New York Academy of Sciences ( IF 4.1 ) Pub Date : 2020-09-06 , DOI: 10.1111/nyas.14467 Eleni Felinska 1 , Adrian Billeter 1 , Felix Nickel 1 , Pietro Contin 1 , Felix Berlth 2 , Bipan Chand 3 , Peter Grimminger 4 , Dean Mikami 5 , Sebastian F Schoppmann 6 , Beat Müller-Stich 1
Annals of the New York Academy of Sciences ( IF 4.1 ) Pub Date : 2020-09-06 , DOI: 10.1111/nyas.14467 Eleni Felinska 1 , Adrian Billeter 1 , Felix Nickel 1 , Pietro Contin 1 , Felix Berlth 2 , Bipan Chand 3 , Peter Grimminger 4 , Dean Mikami 5 , Sebastian F Schoppmann 6 , Beat Müller-Stich 1
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Gastroesophageal reflux disease (GERD), a prevalent problem among obese individuals, is strongly associated with obesity and weight loss. Hence, bariatric surgery effectively improves GERD for many patients. Depending on the type of bariatric procedure, however, surgery can also worsen or even cause a new onset of GERD. As a consequence, GERD remains a relevant problem for many bariatric patients, and especially those who have undergone sleeve gastrectomy (SG). Affected patients report not only a decrease in physical functioning but also suffer from mental and emotional problems, resulting in poorer social functioning. The pathomechanism of GERD after SG is most likely multifactorial and triggered by the interaction of anatomical, physiological, and physical factors. Contributing factors include the shape of the sleeve, the extent of injury to the lower esophageal sphincter, and the presence of hiatal hernia. In order to successfully treat post‐sleeve gastrectomy GERD, the cause of the problem must first be identified. Therapeutic approaches include lifestyle changes, medication, interventional treatment, and/or revisional surgery.
中文翻译：
我们了解袖状胃切除术后 GERD 的病理生理学吗？
胃食管反流病 (GERD) 是肥胖个体的普遍问题，与肥胖和体重减轻密切相关。因此，减肥手术有效地改善了许多患者的 GERD。然而，根据减肥手术的类型，手术也会恶化甚至导致新的 GERD 发作。因此，GERD 仍然是许多减肥患者的相关问题，尤其是那些接受过袖状胃切除术 (SG) 的患者。受影响的患者不仅报告身体机能下降，而且还遭受精神和情绪问题，导致社交功能变差。SG 后 GERD 的发病机制很可能是多因素的，由解剖、生理和物理因素的相互作用触发。影响因素包括袖子的形状，食管下括约肌的损伤程度，以及食管裂孔疝的存在。为了成功治疗袖状胃切除术后 GERD，必须首先确定问题的原因。治疗方法包括改变生活方式、药物治疗、介入治疗和/或修复手术。
更新日期：2020-09-06
中文翻译：
我们了解袖状胃切除术后 GERD 的病理生理学吗？
胃食管反流病 (GERD) 是肥胖个体的普遍问题，与肥胖和体重减轻密切相关。因此，减肥手术有效地改善了许多患者的 GERD。然而，根据减肥手术的类型，手术也会恶化甚至导致新的 GERD 发作。因此，GERD 仍然是许多减肥患者的相关问题，尤其是那些接受过袖状胃切除术 (SG) 的患者。受影响的患者不仅报告身体机能下降，而且还遭受精神和情绪问题，导致社交功能变差。SG 后 GERD 的发病机制很可能是多因素的，由解剖、生理和物理因素的相互作用触发。影响因素包括袖子的形状，食管下括约肌的损伤程度，以及食管裂孔疝的存在。为了成功治疗袖状胃切除术后 GERD，必须首先确定问题的原因。治疗方法包括改变生活方式、药物治疗、介入治疗和/或修复手术。
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