Cellulose acetate (CA) microfiltration membranes were fabricated by a combined vapor-induced and wet phase separation technique. A systematic morphology study was performed on the membranes prepared under different fabrication conditions and dope solution compositions. The results showed that symmetric CA membranes could be obtained by controlling relative humidity, temperature and exposure time during vapor-induced phase separation step. While the surface morphology and pore size of the membranes could be mainly tailored by adjusting the dope solution composition. The performance study of the membranes showed that for operation at low transmembrane pressures, only symmetric membranes fabricated by vapor-induced phase separation process have permeability which can be reached 100 L/m²h using polyvinylpyrrolidone with an average molecular weight of 30,000 (PVPK30) or polyethylene glycol with an average molecular weight of 400 (PEG400) as additives. Bacteria removal performance of the membranes showed that samples prepared at optimized solution compositions of CA/PVP and CA/PEG fabricated at constant vapor-induced phase separation (VIPS) condition of 5 min exposure time, 45 °C and 55% relative humidity can completely filtrate the E. coli bacteria. The prepared CA membranes showed no cytotoxicity in mouse L929 fibroblast cells, confirming their biocompatible nature for possible water treatment or biomedical applications.

醋酸纤维素（CA）微滤膜是通过结合气相诱导和湿相分离技术制造的。对在不同制备条件和涂料溶液组成下制备的膜进行了系统的形态学研究。结果表明，通过控制气相诱导相分离过程中的相对湿度，温度和暴露时间，可以获得对称的CA膜。虽然膜的表面形态和孔径可以主要通过调节涂料溶液的组成来调整。膜的性能研究表明，在低跨膜压力下运行时，只有通过气相诱导相分离法制备的对称膜的渗透率才能达到100 L / m ^2。h使用平均分子量为30,000的聚乙烯吡咯烷酮（PVPK30）或平均分子量为400的聚乙二醇（PEG400）作为添加剂。膜的细菌去除性能表明，在5分钟的暴露时间，45°C和55％相对湿度的恒定气相诱导相分离（VIPS）条件下，在CA / PVP和CA / PEG的最佳溶液组成下制备的样品可以完全过滤大肠杆菌。制备的CA膜对小鼠L929成纤维细胞没有细胞毒性，从而证实了它们的生物相容性，可用于水处理或生物医学应用。